Related Experiment Video For HOV
Updated: Jan 24, 2026

Cell-Free DNA Integrity Analysis in Urine Samples
Published on: January 5, 2017
Comparative analysis of 13 HPV genotypes diagnosed in urine sediment cells vs. desquamated cervical epithelial cells
Magdalena Anna Owczarek1, Tadeusz Kałużewski1, Dorota Kucharska1
1Laboratory of Medical Genetics of the “Genos” Partnership R&D Division, Member of the Polish Technological Platform of Innovative Medicine of the National Centre of Research & Development
Introduction:
The human papilloma virus (HPV) belongs to double-stranded, DNA circular viruses which infect the epithelial cells. The highest incidence of HPV is identified in malignant processes which affect the uterine cervix, as well as vulvar, penile, rectal and pharyngeal regions.
Goal Of Study:
An attempt to find correlations between HPV incidence rates in urine sediment cells and in desquamated epithelial cells of the uterine cervix in a group of patients with frequent, recurrent cystitis.
Materials And Methods:
HPV presence was studied, both in urine sediment cells and in uterine cervix epithelial cells of 77 patients.
Results:
An analysis of urinary sediments brought a total of twenty (25.97%) positive and 57 (74.03%) negative results. In turn, an evaluation of uterine cervix material samples revealed 17 (22.08%) positive and 60 (77.92%) negative results.
Conclusions:
The study enabled a comparison between HPV prevalence rates in urine sediment cells and in uterine cervix epithelial cells of an examined patient. The performed observations are likely to trigger a further analysis of the studied issue; however, the obtained results provide arguments for different natural histories of the infection processes.
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