Long-term Israeli Single-Center Experience with the Percutaneous MitraClip Procedure

Shmuel Schwartzenberg1, Ran Kornowski1, Yaron Shapira1

  • 1Department of Cardiology, Rabin Medical Center (Beilinson Campus), Petah Tikva, affiliated with Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Abstract

Insights

The MitraClip procedure offers a viable treatment for severe mitral regurgitation (MR), showing modest improvements in patient function and pulmonary pressure with low procedural risks.

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Medical Devices

Background:

  • The MitraClip procedure is an emerging alternative for high-risk patients suffering from mitral regurgitation (MR).
  • This minimally invasive approach is suitable for both functional MR (FMR) and degenerative MR (DMR) when specific mitral valve anatomy is present.

Purpose of the Study:

  • To assess the outcomes of the MitraClip procedure at our institution.
  • Focus on carefully selected patients with severe mitral regurgitation.

Main Methods:

  • Retrospective analysis of medical records and echocardiography data.
  • Data collected from January 2012 to December 2017.
  • Involved 39 MitraClip procedures in 37 patients.

Main Results:

  • 86.1% of patients achieved moderate to low mitral regurgitation post-procedure, with an 88.8% immediate device success rate.
  • One-year survival was 86%, with functional status (NYHA class) improving in 37% of patients.
  • Systolic pulmonary pressure decreased significantly at 1 month and remained reduced at 12 months.

Conclusions:

  • MitraClip provides a modest improvement in functional status and pulmonary pressure for severe MR patients.
  • The procedure carries a small risk of immediate complications, with encouraging outcomes compared to surgical intervention risks.

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