Related Experiment Video
Updated: Jan 24, 2026

Cox-Maze IV Procedure Concomitant with Valvular Surgery In Situs Inversus Dextrocardia: A Single-Center Experience in China
Published on: February 11, 2022
Long-term Israeli Single-Center Experience with the Percutaneous MitraClip Procedure
Shmuel Schwartzenberg1, Ran Kornowski1, Yaron Shapira1
1Department of Cardiology, Rabin Medical Center (Beilinson Campus), Petah Tikva, affiliated with Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Background:
The MitraClip procedure is becoming an acceptable alternative for high-risk patients with mitral regurgitation (MR) due to functional (FMR) or degenerative (DMR) disease and suitable mitral anatomy.
Objectives:
To evaluate the results of MitraClip at our institute in carefully selected patients.
Methods:
We conducted a retrospective analysis of medical records and echocardiography data from January 2012 to December 2017.
Results:
A total of 39 MitraClip procedures in 37 patients (aged 75 ± 12 years, 9 women) was performed. Twenty-four patients presented with FMR, 12 with DMR, and 1 with combined pathology. One-day post-procedure MR was moderate to low in 86.1% of patients, with immediate device success in 88.8%. MR at 1 year was moderate to low in 79% at 1 year. Survival at 1 year was 86% and at 2 years 69.4%. Peri-procedural (< 1 week) death and MitraClip failure occurred in one and three patients, respectively. New York Heart Association score improved to class 1 or 2 in 37% of patients at 1 year vs. one patient at baseline. Post-procedural systolic pulmonary pressure was reduced from 53 (range 48-65) to 43 (range 36-52) mmHg at 1 month with a subsequent plateau at follow-up, to 41 (34-57) mmHg at 6 months, and to 47 (38-50) at 12 months.
Conclusions:
MitraClip in severe MR resulted in modest improvement in functional status and pulmonary pressure with a small risk of immediate procedural complications. Outcomes are encouraging considering the natural course of MR and the risks of surgical intervention.
Insights
The MitraClip procedure offers a viable treatment for severe mitral regurgitation (MR), showing modest improvements in patient function and pulmonary pressure with low procedural risks.
Area of Science:
- Cardiology
- Interventional Cardiology
- Medical Devices
Background:
- The MitraClip procedure is an emerging alternative for high-risk patients suffering from mitral regurgitation (MR).
- This minimally invasive approach is suitable for both functional MR (FMR) and degenerative MR (DMR) when specific mitral valve anatomy is present.
Purpose of the Study:
- To assess the outcomes of the MitraClip procedure at our institution.
- Focus on carefully selected patients with severe mitral regurgitation.
Main Methods:
- Retrospective analysis of medical records and echocardiography data.
- Data collected from January 2012 to December 2017.
- Involved 39 MitraClip procedures in 37 patients.
Main Results:
- 86.1% of patients achieved moderate to low mitral regurgitation post-procedure, with an 88.8% immediate device success rate.
- One-year survival was 86%, with functional status (NYHA class) improving in 37% of patients.
- Systolic pulmonary pressure decreased significantly at 1 month and remained reduced at 12 months.
Conclusions:
- MitraClip provides a modest improvement in functional status and pulmonary pressure for severe MR patients.
- The procedure carries a small risk of immediate complications, with encouraging outcomes compared to surgical intervention risks.
Related Concept Videos
Lattice Centering and Coordination Number
Types of Unit Cells
Imagine taking a large number of identical...
Center of Gravity
Center of Gravity
To determine its location, the principle of moments can be utilized by dividing the object into...
Center of Mass
The knowledge of the center of mass can also help us to describe and predict the motion of objects. For example, when a ball is thrown...
Long-term Depression
Blind Procedures

