Related Experiment Video

Updated: Jan 24, 2026

A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting
14:43

A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting

Published on: January 12, 2018

12.5K

The Association between Dyslipidemia and Preterm Birth: A Prospective Cohort Study in The North of Iran

Seyedeh H Sharami1, Mahboobeh Gholipour2, Forozan Milani1

  • 1Department of Obstetrics & Gynecology, Reproductive Health Research Center, Azzhra Hospital, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran.

Endocrine, Metabolic & Immune Disorders Drug Targets
|May 31, 2019
PubMed

Insights

Dyslipidemia, including high triglycerides and total cholesterol, is linked to preterm birth (PTB). Managing lipid profiles during pregnancy may help reduce PTB risk.

Area of Science:

  • Obstetrics and Gynecology
  • Cardiovascular Health
  • Neonatal Health

Background:

  • Dyslipidemia is a significant risk factor for preterm birth (PTB).
  • Early identification of PTB risk factors is crucial for reducing maternal and neonatal complications.

Purpose of the Study:

  • To investigate the association between dyslipidemia and PTB in pregnant women in Iran's Guilan province.

Main Methods:

  • Prospective cohort study of 378 pregnant women in Rasht city.
  • Analysis of lipid profiles: Total Cholesterol (TC), HDL, LDL, and Triglycerides (TG).
  • Statistical assessment using Chi-square, Fisher tests, and logistic regression.

Main Results:

  • Triglycerides (TG) and Total Cholesterol (TC) showed high predictive power for PTB (AUC=0.833 and 0.772).
  • Sensitivity and specificity for TG and TC were 83.3% and 70.2%, and 83.3% and 66.1%, respectively.
  • Abnormal LDL concentrations were associated with a twofold increased risk of PTB (P < 0.05).

Conclusions:

  • Controlling maternal lipid profiles may be an effective strategy to reduce the incidence of preterm birth.
  • Dyslipidemia markers are important indicators for PTB risk assessment.
Abstract

Keywords:
DyslipidemiaIranpregnancypreterm birthprospective cohort studytriglycerideswomen.

More Related Videos

Modeling Ascending Vaginal Infection, Preterm Birth, and Neonatal Morbidity in Mice04:18

Modeling Ascending Vaginal Infection, Preterm Birth, and Neonatal Morbidity in Mice

Published on: October 10, 2025

386
Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry05:53

Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry

Published on: June 21, 2018

10.6K

Related Concept Videos

Birth Control Methods01:22

Birth Control Methods

Vasectomy is a surgical form of male sterilization that involves severing and sealing the vasa deferentia, preventing sperm from mixing with semen during ejaculation. Because a vasectomy does not impact the testes' ability to produce testosterone, hormone levels, libido, and sexual function generally remain unchanged. While vasectomy is highly effective in preventing pregnancy, with a success rate near 99.85%, rare cases of recanalization (spontaneous reconnection) can occur. Although...
5.9K
Genome-wide Association Studies-GWAS01:11

Genome-wide Association Studies-GWAS

Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
15.4K
Association Areas of the Cortex01:21

Association Areas of the Cortex

Association areas are regions of the cerebral cortex that do not have a specific sensory or motor function. Instead, they integrate and interpret information from various sources to enable higher cognitive processes such as memory, learning, and decision-making. Some key association areas include the following:
Prefrontal Association Area: This area is located in the frontal lobe and is involved in planning, decision-making, and moderating social behavior. It connects with primary motor areas,...
9.1K
Associative Learning01:27

Associative Learning

Associative learning is a fundamental concept in behavioral psychology, wherein a connection is established between two stimuli or events, leading to a learned response. This process is critical in understanding how behaviors are acquired and modified. Conditioning, the mechanism through which associations are formed, can be divided into two main types: classical conditioning and operant conditioning, each elucidating different aspects of associative learning.
Classical conditioning, also known...
1.3K
Somatosensory, Motor, and Association Cortex01:23

Somatosensory, Motor, and Association Cortex

The somatosensory cortex in the parietal lobes is crucial for interpreting sensory data such as touch, temperature, and proprioception. The somatosensory cortex, situated in the parietal lobes, plays a vital role in interpreting sensory information like touch, temperature, and proprioception—awareness of body position. This specialized brain region features an organized structure wherein neurons at the top primarily process sensations originating from the lower body. In contrast, those at...
2.5K
Case Studies01:22

Case Studies

There are many research methods available to psychologists in their efforts to understand, describe, and explain behavior and the cognitive and biological processes that underlie it.
13.4K