Function-Preserving Multimodal Treatment for Jugular Foramen Meningiomas

Area of Science:

• Neurosurgery
• Oncology
• Radiology

Background:

• Jugular foramen meningiomas (JFMs) are benign but can be locally aggressive.
• Radical surgical removal often leads to lower cranial nerve (LCN) deficits due to the complex anatomy.

Purpose of the Study:

• To evaluate the efficacy of function-preserving multimodal treatment (FMT) for JFMs.
• To achieve long-standing tumor control while preserving LCN function.

Main Methods:

• FMT involved intradural tumor removal preserving LCN function, followed by stereotactic radiosurgery (RS) for residual tumors.
• Six patients with JFMs were studied, with five initially showing no LCN deficits.

Main Results:

• All patients underwent successful function-preserving retrosigmoid intradural tumor removal without new LCN deficits.
• Three patients received RS for residual tumors, achieving complete tumor control.
• No tumor recurrence or new LCN deficits were observed during follow-up (2 months to 8 years).

Conclusions:

• FMT is an effective strategy for managing JFMs.
• This approach offers long-standing tumor control and excellent functional outcomes for patients.