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Published on: February 5, 2014
Evaluation of the practice of dose-rounding in paediatrics
Asia N Rashed1,2, Stephen Tomlin1,2, Sara Arenas-López2
1Institute of Pharmaceutical Science, King's College London, London, UK.
Objectives:
To investigate the rounding of prescribed drug doses for paediatric administration.
Methods:
A cross-sectional medication chart review was conducted at a UK paediatric hospital. Proposed administration dose volumes were calculated for prescribed doses using available manufactured liquids measured with oral and intravenous syringes. Resulting percentage deviations in doses administered were calculated.
Results:
Of 2031 doses observed, 524 (25.8%) required rounding. The majority of which were for children aged 1-12 months. Twenty-seven rounded doses deviated from the prescribed dose by more than 10%.
Conclusion:
This study highlights the impact of dose-rounding in paediatrics and the need for standardisation.
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