The Relationship Between Circulating Interleukin-6 Levels and Future Health Service Use in Dementia Caregivers

Brent T Mausbach1, Gabrielle Decastro, Carlos Vara-Garcia

  • 1From the Department of Psychiatry (Mausbach, Dimsdale, Mills, Patterson, Ancoli-Israel, Grant), University of California San Diego, La Jolla; Department of Psychology (Decastro), San Diego State University, California; Department of Psychology (Vara-Garcia), University Rey Juan Carlos, Madrid, Spain; Joint Doctoral Program in Clinical Psychology (Bos), San Diego State University and University of California San Diego; Department of Consultation-Liaison Psychiatry and Psychosomatic Medicine (von Känel), University Hospital Zurich, Switzerland; Departments of Medicine (Ziegler) and Family and Preventive Medicine (Allison, Mills); and Department of Family Medicine and Public Health (Pruitt), University of California San Diego, La Jolla.

Summary

Elevated Interleukin-6 (IL-6) levels significantly increase emergency department (ED) visit risk for dementia caregivers. High IL-6 and caregiver demands predict vulnerability, suggesting interventions targeting inflammation may prevent ED use.

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