Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

The Thyroid Gland

The Thyroid Gland

The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...

Functions of Thyroid Hormones

Functions of Thyroid Hormones

The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...

Synthesis and Regulation of Thyroid Hormones

Synthesis and Regulation of Thyroid Hormones

Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...

Relative Risk

Relative Risk

Relative risk (RR) is a statistical measure commonly used in epidemiology to compare the likelihood of a particular event occurring between two groups. This metric is important for evaluating the relationship between exposure to a specific risk factor and the probability of a particular outcome. It plays a crucial role in medical research, public health studies, and risk assessment. Relative risk quantifies how much more (or less) likely an event is to occur in an exposed group compared to an...

Factors Affecting the Risk of Infection

Factors Affecting the Risk of Infection

The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...

Co-activators and Co-repressors

Co-activators and Co-repressors

Gene transcription is regulated by the synergistic action of several proteins that form a complex at a gene regulatory site. This is observed in eukaryotes, where the regulation of gene expression is a complex process. Regulatory proteins in eukaryotes can broadly be classified into two types – regulators that bind directly to specific DNA sequences and co-regulators that associate with regulatory proteins but cannot directly bind to the DNA. These co-regulators are further divided into...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Implementation of delayed intervention in open approach rhinoplasty for patients with supratip scarring.

Annales de chirurgie plastique et esthetique·2024

Same author

Quantitative ultrasound techniques and biochemical markers to assess liver steatosis and fibrosis in newly diagnosed acromegaly.

Journal of endocrinological investigation·2024

Same author

ASSOCIATION BETWEEN HASHIMOTO'S THYROIDITIS AND PAPILLARY THYROID CANCER: A SINGLE CENTER EXPERIENCE.

Acta endocrinologica (Bucharest, Romania : 2005)·2022

Same author

Asymmetry indicates more severe and active disease in Graves' orbitopathy: results from a prospective cross-sectional multicentre study.

Journal of endocrinological investigation·2020

Same author

Successful Treatment of Renal Infiltration Complicated by Atypical Hemolytic Uremic Syndrome in a Leukemic Child.

Indian journal of nephrology·2018

Same author

Association of serum betatrophin with fibroblast growth factor-21 in women with polycystic ovary syndrome.

Journal of endocrinological investigation·2018

Search research articles

Related Experiment Video

Updated: Jan 24, 2026

Spontaneous Murine Model of Anaplastic Thyroid Cancer

Spontaneous Murine Model of Anaplastic Thyroid Cancer

Published on: February 3, 2023

THYROID MALIGNANCY RISK OF INCIDENTAL THYROID NODULES IN PATIENTS WITH NON-THYROID CANCER.

M M Yalcin¹, A E Altinova¹, C Ozkan¹

¹Gazi University Faculty of Medicine, Department of Endocrinology and Metabolism, Ankara, Turkey.

Acta Endocrinologica (Bucharest, Romania : 2005)

|June 1, 2019

Summary

Thyroid incidentalomas in patients with non-thyroid cancer show a low risk of malignancy. Further evaluation is needed to understand the precise cancer risk in these specific cases.

Keywords:

non-thyroid cancer thyroid cancer thyroid nodules

More Related Videos

A Swin Transformer-Based Model for Thyroid Nodule Detection in Ultrasound Images

A Swin Transformer-Based Model for Thyroid Nodule Detection in Ultrasound Images

Published on: April 21, 2023

Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model

Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model

Published on: March 17, 2023

Related Experiment Videos

Last Updated: Jan 24, 2026

Spontaneous Murine Model of Anaplastic Thyroid Cancer

Spontaneous Murine Model of Anaplastic Thyroid Cancer

Published on: February 3, 2023

A Swin Transformer-Based Model for Thyroid Nodule Detection in Ultrasound Images

A Swin Transformer-Based Model for Thyroid Nodule Detection in Ultrasound Images

Published on: April 21, 2023

Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model

Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model

Published on: March 17, 2023

Area of Science:

Endocrinology
Oncology
Pathology

Background:

Thyroid incidentalomas are frequently encountered in clinical practice.
Limited data exists on the risk of thyroid cancer in patients with pre-existing non-thyroidal cancers.

Purpose of the Study:

To determine the frequency of thyroid malignancy in incidental thyroid nodules found in patients with a history of non-thyroid cancer.

Main Methods:

Retrospective evaluation of 287 thyroid nodules from 161 patients with non-thyroid cancer history (2008-2014).
Analysis of fine needle aspiration biopsy results and surgical histopathology for malignancy.

Main Results:

69.7% of nodules were benign by cytology.
Thyroid cancer was confirmed in 3 surgically removed nodules (11.1% of operated nodules, excluding metastasis and incidental findings).
Metastasis from non-thyroid cancer to the thyroid occurred in 4 nodules.

Conclusions:

The risk of thyroid malignancy in incidental thyroid nodules appears not significantly elevated in patients with non-thyroid cancer.
A nodule-based assessment suggests a low cancer risk in this population.