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MUSCULAR HYPERTROPHY AS ATYPICAL INITIAL PRESENTATION OF HYPOTHYROIDISM
H Aydın1, H A Fındıklı1, A S Tutak1
1Adıyaman University Training and Research Hospital, Dept. of Internal Medicine, Adıyaman, Turkey.
Summary
Hypothyroidism can cause muscle problems, including rare Hoffmann's syndrome with muscle hypertrophy and stiffness. Early diagnosis and hormone replacement therapy lead to excellent recovery.
Area of Science:
- Endocrinology
- Neurology
- Musculoskeletal Diseases
Background:
- Hypothyroidism is a common endocrine disorder with diverse symptoms.
- Myopathic changes affect 30-80% of hypothyroidism patients, but muscular hypertrophy is rare (<10%).
- Hoffmann's syndrome, a rare hypothyroid myopathy, presents with muscle hypertrophy, stiffness, and elevated enzymes.
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