Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Diabetes Mellitus: Type 2 and Gestational

Diabetes Mellitus: Type 2 and Gestational

Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...

Diabetes Mellitus: Overview and Type I Subtype

Diabetes Mellitus: Overview and Type I Subtype

Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...

Pathophysiology of Diabetes

Pathophysiology of Diabetes

Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...

Diabetes: Management and Pharmacotherapy

Diabetes: Management and Pharmacotherapy

The therapy for diabetes aims to alleviate hyperglycemia-related symptoms, prevent acute metabolic decompensation, and reduce chronic end-organ complications. Glycemic control is evaluated through short-term (self-monitoring, continuous glucose monitoring) and long-term (A1c, fructosamine) metrics, enabling near real-time tracking of blood glucose levels and reflecting glycemic control over specific time frames.
Insulin remains the cornerstone of treatment for most patients with type 1 and many...

Psychoneuroimmunology: Diabetes and Cancer

Psychoneuroimmunology: Diabetes and Cancer

Chronic stress has been linked to both the onset and progression of serious health conditions, including Type 2 diabetes and cancer. Type 2 diabetes, a widespread chronic illness, is closely associated with obesity and insulin resistance, both of which often worsen under stress. Studies indicate that men experiencing high levels of chronic stress face a 45% higher risk of developing diabetes compared to those with minimal stress. Stress triggers physiological responses that elevate blood...

Diabetes: Symptoms, Diagnosis, and Complications

Diabetes: Symptoms, Diagnosis, and Complications

For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Gastrointestinal toxicity of systemic oncology immunotherapy.

Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti·2022

Same author

High resolution anorectal manometry in patients with anorectal dysfunctions and the therapeutic consequences.

Rozhledy v chirurgii : mesicnik Ceskoslovenske chirurgicke spolecnosti·2022

Same author

Pathophysiological Characteristics Linking Type 2 Diabetes Mellitus and Colorectal Neoplasia.

Physiological research·2021

Same author

Zenkers diverticulum - effectiveness of endoscopic therapy.

Rozhledy v chirurgii : mesicnik Ceskoslovenske chirurgicke spolecnosti·2020

Same author

Update and review of diagnosing functional anorectal disorders - standardized protocol for high-resolution anorectal manometry and the London classification.

Rozhledy v chirurgii : mesicnik Ceskoslovenske chirurgicke spolecnosti·2020

Same author

3D high-resolution anorectal manometry selected case reports.

Rozhledy v chirurgii : mesicnik Ceskoslovenske chirurgicke spolecnosti·2020

Search research articles

Related Experiment Video

Updated: Jan 24, 2026

A Zebrafish Model of Diabetes Mellitus and Metabolic Memory

A Zebrafish Model of Diabetes Mellitus and Metabolic Memory

Published on: February 28, 2013

DIABETIC KETOACIDOSIS WITH AN ACUTE ABDOMEN AS A FIRST MANIFESTATION OF TYPE 1 DIABETES MELLITUS.

J Csomor¹, J Jirkovska¹, L Vedralova¹

¹Charles University and Military University Hospital, 1 Faculty of Medicine, Department of Internal Medicine, Prague, Czech Republic.

Acta Endocrinologica (Bucharest, Romania : 2005)

|June 1, 2019

Summary

Diabetic pseudoperitonitis, a rare type 1 diabetes mellitus complication, can mimic acute abdomen. Early recognition of this diabetic ketoacidosis sign can prevent unnecessary emergency surgery.

Keywords:

Diabetic pseudoperitonitis acute abdomen type 1 diabetes

More Related Videos

A Protocol for Constructing a Rat Wound Model of Type 1 Diabetes

A Protocol for Constructing a Rat Wound Model of Type 1 Diabetes

Published on: February 17, 2023

A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19

A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19

Published on: July 5, 2022

Related Experiment Videos

Last Updated: Jan 24, 2026

A Zebrafish Model of Diabetes Mellitus and Metabolic Memory

A Zebrafish Model of Diabetes Mellitus and Metabolic Memory

Published on: February 28, 2013

A Protocol for Constructing a Rat Wound Model of Type 1 Diabetes

A Protocol for Constructing a Rat Wound Model of Type 1 Diabetes

Published on: February 17, 2023

A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19

A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19

Published on: July 5, 2022

Area of Science:

Endocrinology
Gastroenterology
Surgical Case Reports

Background:

Diabetic pseudoperitonitis is a rare complication of type 1 diabetes mellitus, often presenting with severe ketoacidosis.
Its pathogenesis remains unclear, but it typically manifests as an acute abdomen, necessitating differential diagnosis from other acute abdominal conditions.

Observation:

A 46-year-old male presented with persistent epigastric pain, initially undiagnosed despite extensive investigations including imaging and endoscopy.
Peritoneal signs led to an indicated emergency surgery, which revealed no intra-abdominal pathology.

Findings:

Post-operative recognition of severe metabolic acidosis, initial hypoglycemia, glycosuria, ketonuria, and elevated glycated hemoglobin confirmed new-onset diabetes mellitus.
These findings, in conjunction with the clinical presentation, led to the diagnosis of diabetic pseudoperitonitis.

Implications:

Diabetic pseudoperitonitis can be the initial presentation of diabetes, mimicking surgical emergencies.
Awareness and prompt recognition of this rare condition are crucial to avoid unnecessary surgical interventions.