Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Weak Base Solutions03:21

Weak Base Solutions

24.9K
Some compounds produce hydroxide ions when dissolved by chemically reacting with water molecules. In all cases, these compounds react only partially and so are classified as weak bases. These types of compounds are also abundant in nature and important commodities in various technologies. For example, global production of the weak base ammonia is typically well over 100 metric tons annually, being widely used as an agricultural fertilizer, a raw material for chemical synthesis of other...
24.9K
Titration of a Weak Acid with a Weak Base01:08

Titration of a Weak Acid with a Weak Base

4.9K
Weak acids and bases do not undergo dissociation completely, and titrations between these two are rarely studied. When such studies are performed, say, for the titration of a weak acid with a weak base, the titration curve plots the change in pH as a function of the volume of base added. Take the titration of acetic acid with ammonia, for instance. During the titration, these two species form ammonium acetate and water, but the pH change is slow and gradual.
As a result, there is no simple...
4.9K
Titration Calculations: Weak Acid - Strong Base03:55

Titration Calculations: Weak Acid - Strong Base

49.1K
Calculating pH for Titration Solutions: Weak Acid/Strong Base
For the titration of 25.00 mL of 0.100 M CH3CO2H with 0.100 M NaOH, the reaction can be represented as:
49.1K
Weak Acid Solutions04:02

Weak Acid Solutions

42.4K
Few compounds act as strong acids. A far greater number of compounds behave as weak acids and only partially react with water, leaving a large majority of dissolved molecules in their original form and generating a relatively small amount of hydronium ions. Weak acids are commonly encountered in nature, being the substances partly responsible for the tangy taste of citrus fruits, the stinging sensation of insect bites, and the unpleasant smells associated with body odor. A familiar example of a...
42.4K
Titration of a Weak Acid with a Strong Base01:30

Titration of a Weak Acid with a Strong Base

4.4K
In titrating a weak acid with a strong base, different calculation methods are applied at various stages. Initially, the pH of a weak acid like acetic acid is calculated using its dissociation constant (Ka) and an ICE table. Upon addition of a strong base such as sodium hydroxide, a buffer forms, and its pH is determined using the Henderson-Hasselbalch equation. As more base is added and the titration reaches the halfway point, the pH becomes equal to the pKa of the acid, indicating equal...
4.4K
Titration of a Weak Base with a Strong Acid01:20

Titration of a Weak Base with a Strong Acid

8.7K
The titration curve of a weak base like ammonia with a strong acid like hydrochloric acid is the mirror image of the titration curve of a weak acid with a strong base.
Using the ICE table and substituting the Kb value, we calculate the initial pH of 50 mL of 0.1 M ammonia to be 11.11. Addition of 25 mL of 0.1 M hydrochloric acid to this solution of ammonia results in a buffer with an equal concentration of ammonia and ammonium ions. The pH of this buffer can be calculated by substituting these...
8.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Screening for HPV infection in exfoliated cervical cells of women from different ethnic groups in Yili, Xinjiang, China.

Scientific reports·2019
Same author

Loss-of-function mutations in FREM2 disrupt eye morphogenesis.

Experimental eye research·2019
Same author

Isolation of Litylenchus coprosma from Coprosma macrocarpa, a new host and distribution in New Zealand.

Zootaxa·2019
Same author

Hydrogen generation and simultaneous removal of Cr(VI) by hydrolysis of NaBH<sub>4</sub> using Fe-Al-Si composite as accelerator.

Chemosphere·2019
Same author

Association of smoking and electronic cigarette use with wheezing and related respiratory symptoms in adults: cross-sectional results from the Population Assessment of Tobacco and Health (PATH) study, wave 2.

Tobacco control·2019
Same author

Label-free and Non-destruction Determination of Single- and Double-Strand DNA based on Quantum Weak Measurement.

Scientific reports·2019
Same journal

RETRACTED: Zhang et al. A Novel Framework for Reconstruction and Imaging of Target Scattering Centers via Wide-Angle Incidence in Radar Networks. <i>Sensors</i> 2025, <i>25</i>, 6802.

Sensors (Basel, Switzerland)·2026
Same journal

Enhancing Unsupervised Multi-Source Domain Adaptation for Person Re-Identification via Mixture of Experts and Graph-Based Relation.

Sensors (Basel, Switzerland)·2026
Same journal

Development of an Instrumented Glove for Palmar Pressure Assessment in Kayakers.

Sensors (Basel, Switzerland)·2026
Same journal

Development and Experimental Validation of an Autonomous IoT-Based Monitoring System for Real-Time Water Quality Assessment in the Amazon River.

Sensors (Basel, Switzerland)·2026
Same journal

Semi-Supervised Adversarial Learning Framework for Controller Area Network Bus Intrusion Detection.

Sensors (Basel, Switzerland)·2026
Same journal

Smart Optimization Method for Safety Signs in Innovative Manufacturing Environments Integrating Industrial Field IoT Sensors and Knowledge Graphs.

Sensors (Basel, Switzerland)·2026
See all related articles

Related Experiment Video

Updated: Jan 24, 2026

Dendrimer-based Uneven Nanopatterns to Locally Control Surface Adhesiveness: A Method to Direct Chondrogenic Differentiation
14:46

Dendrimer-based Uneven Nanopatterns to Locally Control Surface Adhesiveness: A Method to Direct Chondrogenic Differentiation

Published on: January 20, 2018

8.2K

A Differential Detection Method Based on a Linear Weak Measurement System.

Nian Xiong1, Tian Guan2,3, Yang Xu4

  • 1College of Information Science and Technology, Jinan University, Guangzhou 510632, Guangdong, China. nancy0122@163.com.

Sensors (Basel, Switzerland)
|June 2, 2019
PubMed
Summary
This summary is machine-generated.

This study introduces a novel differential detection method for biosensors using linear total internal reflection weak measurement. The system demonstrates high stability and enables label-free detection, enhancing biosensor capabilities.

Keywords:
differential detectionlinear systemweak measurement

More Related Videos

Segmentation and Linear Measurement for Body Composition Analysis using Slice-O-Matic and Horos
13:35

Segmentation and Linear Measurement for Body Composition Analysis using Slice-O-Matic and Horos

Published on: March 21, 2021

11.7K
Experimental Methods for Investigation of Shape Memory Based Elastocaloric Cooling Processes and Model Validation
11:11

Experimental Methods for Investigation of Shape Memory Based Elastocaloric Cooling Processes and Model Validation

Published on: May 2, 2016

11.6K

Related Experiment Videos

Last Updated: Jan 24, 2026

Dendrimer-based Uneven Nanopatterns to Locally Control Surface Adhesiveness: A Method to Direct Chondrogenic Differentiation
14:46

Dendrimer-based Uneven Nanopatterns to Locally Control Surface Adhesiveness: A Method to Direct Chondrogenic Differentiation

Published on: January 20, 2018

8.2K
Segmentation and Linear Measurement for Body Composition Analysis using Slice-O-Matic and Horos
13:35

Segmentation and Linear Measurement for Body Composition Analysis using Slice-O-Matic and Horos

Published on: March 21, 2021

11.7K
Experimental Methods for Investigation of Shape Memory Based Elastocaloric Cooling Processes and Model Validation
11:11

Experimental Methods for Investigation of Shape Memory Based Elastocaloric Cooling Processes and Model Validation

Published on: May 2, 2016

11.6K

Area of Science:

  • Optics
  • Biosensing Technology
  • Physical Chemistry

Background:

  • Self-reference detection is crucial for biosensor accuracy.
  • Linear weak measurement systems offer stability, label-free detection, and integration advantages.
  • Existing systems lack robust differential measurement capabilities.

Purpose of the Study:

  • To propose and validate a differential detection method for biosensors.
  • To enhance the stability and performance of linear total internal reflection weak measurement systems.
  • To provide a new approach for real-time biosensing.

Main Methods:

  • Implementation of a linear total internal reflection weak measurement system.
  • Introduction of a half-wave plate (HWP) for light polarization conversion.
  • Measurement of phase change differences in optical paths.

Main Results:

  • Successful demonstration of differential detection.
  • Achieved high stability in the proposed system.
  • Validated the system's effectiveness for biosensing applications.

Conclusions:

  • The proposed linear differential weak measurement system offers a novel method for real-time biosensors.
  • The system enhances stability and provides label-free detection.
  • This work expands the range of available weak measurement sensors.