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Selection of patch test materials for gold allergy.

J F Fowler1

  • 1University of Louisville, School of Medicine, Division of Dermatology, Kentucky 40292.

Contact Dermatitis
|July 1, 1987
PubMed
Summary
This summary is machine-generated.

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Allergic contact dermatitis to gold is rare. Gold sodium thiosulfate is a reliable and non-irritant patch test reagent, unlike gold chloride which can cause persistent reactions.

Area of Science:

  • Dermatology
  • Allergology
  • Toxicology

Background:

  • Allergic contact dermatitis to gold is infrequently documented.
  • Recent cases highlight the need to re-evaluate diagnostic methods.
  • Standard patch testing reagents require careful consideration for safety and efficacy.

Purpose of the Study:

  • To review the literature on gold allergy.
  • To identify optimal reagents for patch testing in suspected gold allergy.
  • To compare the safety and efficacy of different gold compounds for diagnostic testing.

Main Methods:

  • Literature review of allergic contact dermatitis to gold.
  • Analysis of patch testing reagents and their properties.
  • Evaluation of patient case data from a clinical department.

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Main Results:

  • Gold chloride, a common patch test reagent, may induce persistent dermatitis.
  • Gold sodium thiosulfate is available as a non-irritant preparation in petrolatum.
  • Gold sodium thiosulfate demonstrates reliability for patch testing.

Conclusions:

  • Gold sodium thiosulfate is recommended as a preferred reagent for patch testing in suspected gold allergy.
  • Avoidance of irritant reagents like gold chloride is advised.
  • Further research into gold allergy diagnostics is warranted.