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MOG antibody-associated demyelinating disease mimicking typical multiple sclerosis: A case for expanding anti-MOG
Marianthi Breza1, Georgios Koutsis1, John S Tzartos2
1Demyelinating Diseases Unit, National and Kapodistrian University of Athens, Medical School, 1st Department of Neurology, Eginition Hospital, Athens, Greece.
Abstract:
MOG-antibody associated demyelinating disease is a new emerging diagnostic entity. Recently, international recommendations for testing of anti-MOG antibodies were published. Herein, we describe a case of anti-MOG antibody-associated demyelinating disease initially diagnosed as typical MS, and, at presentation, not fulfilling the proposed recommendations. This case highlights the expanding spectrum of anti-MOG antibody-associated demyelinating disease, illustrating the distinct and overlapping features of MS and MOG-antibody associated demyelinating disease, providing evidence that on rare occasions these recommendations may prove too restrictive.
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