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Updated: Jan 23, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
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Association of Psoriasis with Psychiatric Hospitalization in United States Children and Adults

Kevin R Patel1, Harrison H Lee1, Supriya Rastogi1

  • 1Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.

Dermatology (Basel, Switzerland)
|June 5, 2019
PubMed

Insights

Individuals with psoriasis experience more mental health (MH) emergencies, leading to increased hospitalizations and significant financial costs. This highlights a critical need for integrated care for psoriasis patients.

Area of Science:

  • Dermatology and Psychiatry
  • Public Health and Health Services Research

Background:

  • Psoriasis is frequently linked to psychosocial distress.
  • The association between psoriasis and mental health (MH) emergencies remains under-explored.

Purpose of the Study:

  • To investigate the relationship between psoriasis and mental health hospitalizations in the United States.
  • To quantify the increased risk and associated costs of MH disorders in psoriasis patients.

Main Methods:

  • Analysis of a large national dataset (National Inpatient Sample) from 2002-2012.
  • Inclusion of approximately 20% of all US hospitalizations, encompassing over 87 million individuals.
  • Multivariable logistic regression models to assess associations, controlling for relevant factors.

Main Results:

  • Psoriasis patients had a higher likelihood of hospitalization for MH disorders (4.04% vs. 2.21%).
  • Psoriasis was associated with 2.32 times higher odds of admission for any MH disorder, including anxiety, depression, and substance use disorders.
  • Psoriasis patients with MH disorders incurred higher inpatient care costs, contributing to an estimated $1.6 million in excess annual costs.

Conclusions:

  • Psoriasis is significantly associated with increased hospitalizations for various mental health disorders in both children and adults.
  • These increased MH hospitalizations represent a substantial financial burden on the healthcare system.
Abstract

Keywords:
Adjustment disorderAnxietyDepressionBurdenConduct disorderCost of careHospitalizationImpulse disorderInpatientLength of stayMental healthMorbidityMortalityPrognosisPsoriasisPsychosisSchizophreniaSuicidality

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