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Rennan Luiz Oliveira Dos Santos1, Carina Domaneschi1, Victhoria Beatriz Pedroso1
1Faculdade de Odontologia, Universidade de São Paulo, São Paulo, SP, Brasil.
Revista Da Sociedade Brasileira De Medicina Tropical
|June 6, 2019
Summary
Surface treatment of acrylic resins with poly(diallyldimethylammonium chloride) demonstrated significant antifungal activity against Candida albicans and Aspergillus niger, enhancing material efficacy for facial prostheses.
Area of Science:
- Biomaterials Science
- Mycology
- Surface Chemistry
Background:
- Acrylic resins are widely used in fabricating facial prostheses.
- These materials are susceptible to fungal colonization, posing a risk to patients.
- Antifungal treatments are crucial for improving the safety and longevity of prostheses.
Purpose of the Study:
- To evaluate the antifungal efficacy of acrylic resin after surface modification.
- To assess the impact of poly(diallyldimethylammonium chloride) treatment on fungal growth inhibition.
Main Methods:
- Acrylic resin specimens were prepared with and without surface treatment.
- Fungistatic and fungicidal tests were conducted using standard strains of Candida albicans and Aspergillus niger.
- Standardized laboratory methods were employed to quantify antifungal activity.
Main Results:
- Surface-treated acrylic resins exhibited significant fungistatic and fungicidal activity against Candida albicans.
- The treatment also demonstrated fungistatic action against Aspergillus niger.
- Untreated acrylic resins showed no significant antifungal properties.
Conclusions:
- Surface treatment with poly(diallyldimethylammonium chloride) effectively imparts antifungal properties to acrylic resins.
- This approach enhances the clinical performance and safety of facial prostheses by preventing fungal colonization.