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ASSOCIATION OF CIRCADIAN RHYTHM WITH MYOCARDIAL INFARCTION

Ivana Škrlec1, Jakov Milić1, Marija Heffer1

  • 11Department of Medical Biology and Genetics, Faculty of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia; 2Department of Biology and Chemistry, Faculty of Dental Medicine and Health, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia; 3Division of Cardiovascular Diseases and Intensive Care, Department of Internal Medicine, Osijek University Hospital Centre, Osijek, Croatia; 4Clinical Institute of Medical Genetics, University Medical Center Ljubljana, Ljubljana, Slovenia.

Acta Clinica Croatica
|June 7, 2019
PubMed

Insights

This study found no link between chronotype or daytime sleepiness and myocardial infarction risk. Cardiovascular disease risk factors like hypertension and diabetes were significant, but sleep patterns were not associated with heart attack susceptibility.

Area of Science:

  • Cardiology
  • Sleep Medicine
  • Chronobiology

Background:

  • Cardiovascular diseases represent a leading global cause of mortality.
  • Circadian rhythms influence human physiological activities and illness states.

Purpose of the Study:

  • To investigate the association between chronotype and daytime sleepiness with myocardial infarction susceptibility.
  • To explore the role of sleep patterns in cardiovascular disease risk.

Main Methods:

  • A case-control study involving 200 myocardial infarction patients and 200 healthy controls.
  • Chronotype assessed via Morningness-Eveningness Questionnaire (MEQ).
  • Daytime sleepiness evaluated using the Epworth Sleepiness Scale (ESS).

Main Results:

  • No significant differences in MEQ or ESS scores were observed between myocardial infarction patients and controls.
  • Significant differences in cardiovascular disease risk factors (hypertension, dyslipidemia, diabetes) were noted.
  • No association found between MEQ/ESS scores and myocardial infarction.

Conclusions:

  • Chronotype and daytime sleepiness do not appear to be directly associated with myocardial infarction in this study population.
  • Traditional cardiovascular risk factors remain critical in myocardial infarction development.
  • Further research may explore complex interactions between circadian rhythm and cardiovascular health.

Keywords:
Cardiovascular diseasesCause of deathCircadian rhythmCroatiaMyocardial infarction

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