[Vasculorenal accidents in pregnancy. Prognostic value of renal biopsy]

Our study is an attempt to determine whether, after a vasculo-renal accident (VRA) in pregnancy, renal biopsy (RB) is of interest to determining the outcome specially of blood pressure. Starting from the 201 RB we systematically performed in such patients we may conclude: first, the onset of clinical and biological troubles do not allow to postulate the existing kidney lesions. Minimal changes observed in 31 women appeared early 9 times and during the last trimester 22 times. Most of the cases observed were preeclampsia (n = 108). The clinical or biological troubles were observed 44 times within the first months of the pregnancy and in 64 patients at the end of it. A specific group isolated concerns predominant vascular lesions (n = 44). Forward troubles were observed 16 times and 28 times during the third trimester. Second: a follow up has been possible for 1 to 5 years in 145 patients. A permanent hypertension occurred out of the 80 preeclamptic women, meanwhile among the 40 women with predominant vascular lesions, 60 p. 100 developed a permanent hypertension. Thus RB provides interesting data on renal lesions revealing sometimes (n = 18) a specific nephropathy (most of them were a glomerulopathy). Furthermore predominant vascular lesions suggest hypertension to recur in later pregnancy or become permanent.