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M Srour1, D Sayag2, S Nghiem-Buffet3

  • 1Département d'ophtalmologie, Centre hospitalier intercommunal de Créteil, 40, avenue de Verdun, 94000 Créteil, France.

Journal Francais D'Ophtalmologie
|June 9, 2019
PubMed
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This summary is machine-generated.

Polypoidal choroidal vasculopathy (PCV) diagnosis relies on multimodal imaging like indocyanine green angiography. Treatment options include anti-VEGF injections or a combination of photodynamic therapy and anti-VEGF, guided by lesion location.

Area of Science:

  • Ophthalmology
  • Medical Imaging
  • Retinal Diseases

Background:

  • Polypoidal choroidal vasculopathy (PCV) is a subtype of age-related macular degeneration.
  • Accurate diagnosis and timely treatment are crucial for preserving vision in PCV patients.

Purpose of the Study:

  • To provide an updated overview of PCV diagnosis and treatment.
  • To propose a treatment algorithm aligned with French market approvals and FFM recommendations.

Main Methods:

  • Comprehensive literature review.
  • Consensus-based expert opinion from the France Macula Federation (FFM).

Main Results:

  • Multimodal imaging, particularly indocyanine green angiography (ICGA), is essential for PCV diagnosis.
Keywords:
Angiographie au vert d’indocyanine (ICGA)Anti-VEGFIndocyanine green angiography (ICGA)Optical coherence tomographyOptical cohérence tomographiePhotodynamic therapy (PDT)Photothérapie dynamique (PDT)Polypoidal Choroidal VasculopathyVasculopathie polypoïdale

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  • First-line treatment recommendations include anti-VEGF monotherapy or a combination of photodynamic therapy (PDT) with Verteporfin and anti-VEGF, depending on PCV location.

    • Conclusions:

    • ICGA remains the gold standard for PCV diagnosis.
    • Treatment strategies for PCV should be tailored based on lesion characteristics and available therapies, as per FFM guidelines.