Identification and assessment of risk factors role in myocardial infarction development

Victor A Ognev1, Anna A Podpriadova1, Anna V Lisova1

  • 1Kharkiv National Medical University, Kharkiv, Ukraine.

Wiadomosci Lekarskie (Warsaw, Poland : 1960)
|June 9, 2019
PubMed

Insights

This study identified 30 significant risk factors for myocardial infarction, with hypertension, hypercholesterolemia, and smoking being the most impactful. Understanding these factors is key to preventing heart attacks.

Area of Science:

  • Cardiology
  • Public Health
  • Epidemiology

Background:

  • Cardiovascular disease (CVD) poses a significant public health challenge due to high morbidity and mortality.
  • Insufficient control over key risk factors contributes to the prevalence of myocardial infarction (MI).
  • Assessing diverse risk factors is crucial for effective CVD prevention strategies.

Purpose of the Study:

  • To comprehensively evaluate the impact of various risk factors on the development of myocardial infarction.
  • Investigate biological, social, economic, psychological, and environmental influences on MI.
  • Identify key determinants for targeted intervention.

Main Methods:

  • A sociological survey was conducted among 500 participants aged 34-85.
  • Participants were divided into two groups: 310 with myocardial infarction and 190 healthy controls.
  • Groups were matched for age, gender, and other relevant parameters.

Main Results:

  • Thirty distinct factors were identified as significantly impacting myocardial infarction development.
  • Biological factors, including hypertension and hypercholesterolemia, were leading contributors.
  • Smoking emerged as the primary socio-hygienic risk factor.

Conclusions:

  • The identification of specific risk factors offers new avenues for MI prevention and treatment.
  • Targeting identified biological and socio-hygienic factors can enhance public health outcomes.
  • Further research into the interplay of all investigated factors is warranted.
Abstract

Related Concept Videos

Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
13.3K
Role of Hematopoietic Growth Factors01:28

Role of Hematopoietic Growth Factors

Hematopoietic growth factors are molecules that regulate the differentiation rate of hematopoietic stem cells (HSCs). Erythropoietin (EPO), primarily produced by the kidneys, plays a crucial role in erythrocyte production. When oxygen levels in the blood are low, EPO is released into the bloodstream, reaching the bone marrow, where it stimulates HSCs to differentiate and mature into erythrocytes, which are vital for oxygen transport.
Thrombopoietin (TPO), mainly released by the liver,...
3.2K
Design Example: Analyzing Capacity Contours for Flood Risk Assessment01:17

Design Example: Analyzing Capacity Contours for Flood Risk Assessment

Flood risk assessment involves careful planning and analysis to ensure the safety of communities near water retention structures. Capacity contours are a vital tool in this process, as they illustrate the potential spread of water at specific levels in a given area. In the context of building a bund across a small valley, these contours play a critical role in evaluating the safety of nearby residential areas.In this example, the bund is intended to store stormwater in the valley. The engineers...
289
Role of Communication in the Nursing Process I: Assessment and Diagnosis01:25

Role of Communication in the Nursing Process I: Assessment and Diagnosis

The nursing process uses scientific reasoning, problem-solving, and critical thinking to guide nurses in providing patients with appropriate care. This process is a systematic approach to recognize, avoid, and treat current or potential health issues while promoting the patient's well-being.
The nursing process considers the patient's emotional and physical well-being. The process can be repeated or stopped at any point if judged essential. Assessment is the first step in the nursing...
5.3K
Relative Risk01:12

Relative Risk

Relative risk (RR) is a statistical measure commonly used in epidemiology to compare the likelihood of a particular event occurring between two groups. This metric is important for evaluating the relationship between exposure to a specific risk factor and the probability of a particular outcome. It plays a crucial role in medical research, public health studies, and risk assessment. Relative risk quantifies how much more (or less) likely an event is to occur in an exposed group compared to an...
2.0K
Transcription Factors02:16

Transcription Factors

Tissue-specific transcription factors contribute to diverse cellular functions in mammals. For example, the gene for beta globin, a major component of hemoglobin, is present in all cells of the body. However, it is only expressed in red blood cells because the transcription factors that can bind to the promoter sequences of the beta globin gene are only expressed in these cells. Tissue-specific transcription factors also ensure that mutations in these factors may impair only the function of...
82.3K