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Updated: Jan 23, 2026

A Multimodal Imaging- and Stimulation-based Method of Evaluating Connectivity-related Brain Excitability in Patients with Epilepsy
Published on: November 13, 2016
Cannabinoids, hippocampal excitability and efficacy for the treatment of epilepsy
Isaac Yao1, Efrat Shavit Stein2, Nicola Maggio3
1Department of Neurology, The Chaim Sheba Medical Center at Tel Hashomer, 52621 Ramat Gan, Israel; Department of Neurology and Neurosurgery, Sackler Faculty of Medicine, Tel Aviv University, 6997801 Tel Aviv, Israel.
Abstract:
Interest in cannabis and its related cannabinoids THC and CBD for use as anti-convulsant therapy has been progressively increasing. While the destigmatization of cannabis and cannabis related research have progressed in the last few decades, there are still many questions that remain unanswered. This review seeks to summarize the progress made in cannabis research in the past four decades and to identify possible directions for future research that are critical for the development of cannabinoid-based therapy in epilepsy.
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