Viral exanthems in children: A great imitator
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Published on: April 28, 2016
Nicole Knöpfel1, Lucero Noguera-Morel2, Irene Latour2
1Department of Pediatric Dermatology, University Children's Hospital Zurich, Zurich, Switzerland; Department of Dermatology, University Children's Hospital Niño Jesús, Madrid, Spain.
Insights
Viral exanthems in children often present with varied skin rashes, sometimes mimicking other illnesses. This review aids in diagnosing challenging cases and guides appropriate testing for pediatric viral diseases.
Area of Science:
- Pediatrics
- Dermatology
- Infectious Diseases
Background:
- Viral exanthems are common in children and usually resolve on their own.
- Accurate diagnosis is crucial for appropriate management and further testing.
- Clinical presentations can be diverse, ranging from typical rashes to atypical forms resembling non-viral conditions.
Purpose of the Study:
- To review viral diseases in children with challenging diagnoses due to overlapping clinical features with non-viral illnesses.
- To provide guidance on differential diagnosis for difficult cases.
- To suggest appropriate diagnostic testing strategies.
Main Methods:
- Literature review focusing on pediatric viral exanthems.
- Analysis of clinical presentations and diagnostic challenges.
- Synthesis of information on differential diagnosis and testing.
Main Results:
- Viral exanthems exhibit a polymorphic spectrum of skin eruptions.
- Atypical presentations can mimic non-viral diseases, posing diagnostic challenges.
- Clinical diagnosis is often possible but requires careful consideration.
Conclusions:
- Early recognition and differentiation of viral exanthems are essential in pediatric care.
- This review offers insights into diagnosing challenging viral exanthems in children.
- Guidance is provided for differential diagnosis and selecting appropriate diagnostic tests.
Abstract:
Viral exanthems are frequent in children and are mostly self-limited. Early recognition and differentiation from other childhood illnesses are important to direct further investigations and treatment initiation. The clinical presentation of viral exanthems in children includes a polymorphic spectrum of skin eruptions ranging from classic viral exanthems to "atypical" presentations that can mimic nonviral diseases; thus, viral exanthems of childhood can be readily diagnosed on clinical grounds, but not rarely do they represent a diagnostic challenge. In this review, we focus on viral diseases in children that may be difficult to diagnose due to their clinical similarities with nonviral diseases, and we offer clues for the differential diagnosis and proper diagnostic testing in such cases.
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