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Conservative Site-specific Recombination and Phase Variation

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Because the DNA segments are cut and reorganized in a direction-specific manner, site-specific recombination has emerged as an efficient genetic engineering technique. Flippase and Cyclization recombinases or Flp and Cre, respectively, are two members of the tyrosine recombinase family derived from bacteriophages, that are used to mediate site-specific DNA insertions, deletions, and targeted expression of proteins in mammalian cell lines.
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Related Experiment Video

Updated: Jan 23, 2026

Identification and Protection of the Recurrent Laryngeal Nerve during Transoral Robotic Thyroidectomy

Identification and Protection of the Recurrent Laryngeal Nerve during Transoral Robotic Thyroidectomy

Published on: October 24, 2025

Multifocal recurrence on the transaxillary robotic thyroidectomy incision.

E Chabrillac¹, S Zerdoud², S Fontaine³

¹Département de chirurgie, Institut Universitaire du Cancer Toulouse - Oncopôle, 1, avenue Irène Joliot-Curie, 31059 Toulouse, France.

European Annals of Otorhinolaryngology, Head and Neck Diseases

|June 11, 2019

Summary

This summary is machine-generated.

Robotic thyroidectomy (RT) for thyroid cancer carries a risk of tumor seeding along the incision, even after adjuvant therapies. Careful patient selection is crucial to mitigate this potential complication.

Area of Science:

Surgical Oncology
Endocrine Surgery

Background:

Robotic thyroidectomy (RT) shows promise but lacks long-term oncological validation.
RT presents unique risks compared to open thyroidectomy (OT).

Keywords:

Dissemination Recurrence on the incision Robotic thyroidectomy Thyroid carcinoma Tumour seeding

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