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Imaging InlC Secretion to Investigate Cellular Infection by the Bacterial Pathogen Listeria monocytogenes
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Switchable Dual-Function and Bioresponsive Materials to Control Bacterial Infections
Mehran Ghasemlou, Fugen Daver, Elena P Ivanova1
1School of Science , RMIT University , Melbourne VIC 3000 , Australia.
ACS Applied Materials & Interfaces
|June 11, 2019
Summary
Dual-function bioresponsive materials offer enhanced protection against bacterial colonization on medical devices. These advanced materials reversibly switch between cell-resistance and biocidal properties for superior biomedical applications.
Area of Science:
- Biomaterials Science
- Surface Chemistry
- Medical Device Engineering
Background:
- Bacterial colonization on biomedical devices is a significant clinical challenge.
- Existing single-function bioresponsive materials (cell-resistance or bactericidal) have limitations.
- Dual-function materials offer improved performance by combining both properties.
Purpose of the Study:
- To review recent advancements in dual-function bioresponsive materials.
- To discuss their design, structure, and fabrication.
- To explore translational challenges and future research directions.
Main Methods:
- Literature review of dual-function bioresponsive materials.
- Analysis of material design, structure, and fabrication techniques.
- Discussion of applications in biomedical devices, tissue engineering, and drug delivery.
Main Results:
- Emergence of dual-function bioresponsive materials capable of reversible switching between cell-resistance and biocidal states.
- These materials show promise for enhanced performance in various biomedical applications.
- Recent progress in design, structure, and fabrication has been highlighted.
Conclusions:
- Dual-function bioresponsive materials represent a significant advancement over single-function materials.
- Their reversible switching capability offers superior solutions for preventing bacterial colonization.
- Further research is needed to address translational challenges and unlock their full potential in clinical settings.
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