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Costo de la intoxicación por Paraquat en Colombia
Jefferson Antonio Buendía1, Gabriel Jaime Restrepo Chavarriaga1
1Grupo de Investigación en farmacología y toxicología, departamento de farmacología y toxicología. Facultad de Medicina, Universidad de Antioquia, Medellín, Antioquia, Colombia.
Introduction:
Paraquat (PQ) poisoning is a public health problem that affects developing countries. The lack of information regarding the economic impact generated by this problem in the country constitutes a barrier to the correct allocation of health priorities.
Objective:
Estimate the annual cost of PQ poisoning in Colombia.
Methods:
A cost-disease study was made, using a decision tree model from the perspective of society, taking an approach based on prevalence. A probabilistic sensitivity analysis was made using the Monte Carlo technique with a simulation of a hypothetical cohort of 10,000 patients intoxicated by PQ.
Results:
An average cost per patient of US$ 2.642 (CI 95% 2.237-6.638 US$) was estimated for acute PQ poisoning. Taking into account the national report during 2017 of 344 cases to national surveillance system; the total cost of PQ poisoning in Colombia amounts to US $ 892 336 per year.
Conclusions:
The average cost per patient intoxicated by PQ exceeds that of various chronic diseases prevalent in our country. This reveals the impact not only clinical, but also economical, of this poisoning in our country, necessitating strategies that regulate commercialization to avoid premature deaths.
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