Related Experiment Video
Updated: Jan 23, 2026

An Adoptive Transfer Model of Rheumatoid Arthritis in Mice
Published on: June 6, 2025
[The severity of rheumatoid arthritis as a timely predictor of instability in the asymptomatic cervical spine]
N A Geraldo-Flores1, R J Merlos-López1, J A Rodríguez-Wong2
1Hospital Regional 2. Instituto Mexicano del Seguro Social (IMSS) Villa Coapa. Ciudad de México, México.
Introduction:
Cervical spine involvement is common in patients with RA, risk factors such as disease activity may be related to asymptomatic cervical instability.
Objective:
To determine the associated factors for asymptomatic cervical spine instability in patients with rheumatoid arthritis.
Material And Methods:
Case and control study from the external spine and rheumatology consultation of a level II trauma center to identify all patients diagnosed with rheumatoid arthritis (RA) and asymptomatic cervical instability. With simple X-rays of the cervical spine, carrying out radiographic measurements, the diagnosis of cervical instability was performed, risk factors such as the presence of rheumatoid factor (FR), previous articular surgeries, elevations of the C-reactive protein (PCR) values were evaluated. The severity and activity of the disease measured in the activity index of 28 articulations (DAS 28) in addition to the index of activity of the simplified disease (SDAI).
Results:
We assessed 32 patients, nine patients (28.1%) met the criteria for instability of the anterior cervical spine atlantoaxial subluxation (SAAa) (100%), also one patient with SAAa presented vertical subluxation (SV), risk factors more relevant: DAS 28 with an OR = 3.54, SDA with an OR = 2.34 and finally the PCR 1.0 its OR = 2.88.
Conclusion:
The risk factors associated opportunely in our population are the severity of the activity of the disease that we can see in the DAS and SDAI when applied in patients and PCR 1.0.
More Related Videos
09:31Generation of Induced-pluripotent Stem Cells Using Fibroblast-like Synoviocytes Isolated from Joints of Rheumatoid Arthritis Patients
Published on: October 16, 2016
07:44Author Spotlight: Implementation of BIVA for Analyzing Disease Risk Factors in Patients with Low Body Cell Mass
Published on: July 14, 2023
Related Concept Videos
Microtubule Instability
Generation Time
Mixing Time
Mean free path and Mean free time
Time Course of Drug Effect
Setting Time of Cement