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Updated: Jan 23, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
Published on: July 11, 2013
Treatment of acrodermatitis continua of hallopeau with ixekizumab
Austinn C Miller1,2, Timothy E Holland1,3, David J Cohen1
1Skin Care Physicians of Georgia, Macon, GA, USA.
Insights
Acrodermatitis continua of Hallopeau (ACH), a rare pustular psoriasis variant, is difficult to treat. This case study shows successful management of therapy-resistant ACH using an IL-17 inhibitor, ixekizumab.
Area of Science:
- Dermatology
- Inflammatory skin diseases
- Psoriasis variants
Background:
- Acrodermatitis continua of Hallopeau (ACH) is a rare, chronic, and inflammatory pustular psoriasis subtype.
- ACH typically affects the digits and is notoriously resistant to standard therapies.
- The lack of established treatment guidelines for ACH poses a clinical challenge.
Abstract:
Acrodermatitis continua of hallopeau (ACH) is a rare chronic inflammatory variant of pustular psoriasis often restricted to the distal portions the digits in the hands and feet. ACH is of a chronic relapsing nature and is invariably recalcitrant to many available topical and systemic anti-psoriatic therapies. On account of its low prevalence and high resistance to treatments, no clinical guideline of ACH exists. We present a patient with ACH resistant to multiple therapies, including the biologic adalimumab, who was successfully treated with an IL-17 inhibitor (ixekizumab). We believe our unique treatment with an excellent outcome may assist other dermatologists if faced with this condition.
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