Related Experiment Videos
Pancreatic perivascular lipid droplets--observations on adverse effects in the rat
1Department of Biochemistry, IV Clinic of General Surgery, Medical Academy, Zabrze, Poland.
Abstract:
A standardized method for the isolation of so-called pancreatis perivascular lipid droplets (PPD) together with cells scattered on their surface is described. After implantation of PPD into the diabetic rat, a long term increase in glycaemia was found. After prior damage to PPD by the actions of enzymes a shortening of the post implantation survival period or even death of recipients within hours was observed. Possibility of participation of PPD in toxic effects observed during pancreatitis is discussed.