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Single-dose piperacillin versus cefoxitin combined with 10 percent mannitol bowel preparation as prophylaxis in
D G Jagelman1, V W Fazio, I C Lavery
1Department of Colorectal Surgery, Cleveland Clinic Foundation, Ohio 44106.
American Journal of Surgery
|November 1, 1987
Abstract:
A prospective, randomized study was utilized to compare the effectiveness of a single dose of preoperative piperacillin versus triple-dose cefoxitin in prophylaxis for elective colorectal operations. All patients received a simple 1 day mechanical bowel preparation using 10 percent mannitol preparation administered orally. Ninety-four patients were entered into the study. Septic complications occurred in 9 percent of the piperacillin patients and in 12 percent of the cefoxitin patients.