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Related Concept Videos

Spinal Cord01:26

Spinal Cord

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The spinal cord, a critical component of the central nervous system, extends from the base of the brainstem to the lumbar region of the vertebral column. It is essential for maintaining physical stability and facilitating communication between the brain and peripheral parts of the body.
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The Spinal Cord01:54

The Spinal Cord

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The spinal cord is the body’s major nerve tract of the central nervous system, communicating afferent sensory information from the periphery to the brain and efferent motor information from the brain to the body. The human spinal cord extends from the hole at the base of the skull, or foramen magnum, to the level of the first or second lumbar vertebra.
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Spinal Cord: Information Processing01:10

Spinal Cord: Information Processing

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The spinal cord is an integral hub for motor and sensory information that enables the brain to communicate with the peripheral nervous system (PNS). This communication consists of relaying sensory data and transmission of motor commands.
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Sensory information processing begins at the sensory receptors located in the skin and other tissues, which detect somatic sensory stimuli such as touch, temperature, or pain. These receptors function as catalysts, initiating...
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Spinal Cord: Gross Anatomy01:15

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The spinal cord resides within the protective confines of the vertebral column. It is the main pathway for information traveling between the brain and the body. It plays a fundamental role in nearly all bodily functions, from simple reflexes to complex motor movements. The spinal cord begins at the medulla oblongata at the base of the brainstem and extends downward, terminating at the conus medullaris near the first and second lumbar vertebrae. The spinal cord's length in adults is...
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Spinal Cord: Cross-sectional Anatomy01:16

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The cross-sectional anatomy of the spinal cord offers a detailed view of its complex structure and function within the central nervous system. At the core of the spinal cord lies the gray matter, characterized by its butterfly or "H"-shaped appearance in cross-section. This central region is enveloped by white matter, with the overall structure divided into symmetrical halves by the dorsal median sulcus and the ventral median fissure.
Gray Matter and its Components
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Behavior of Concrete Under Compressive Load01:23

Behavior of Concrete Under Compressive Load

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Concrete exhibits specific behaviors under different compressive loads. Understanding this is crucial for understanding its structural integrity. When concrete undergoes uniaxial compression, it tends to develop cracks that run parallel to the direction of the force. These parallel cracks stem from localized tensile stresses that occur perpendicular to the compression direction. Additionally, angled cracks may appear due to the formation of shear planes.
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Calibrated Forceps Model of Spinal Cord Compression Injury
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Malignant spinal cord compression.

A Graham Macdonald1, Daniel Lynch2, Ian Garbett3

  • 1Clinic D, Aberdeen Royal Infirmary, Foresterhill, Aberdeen AB25 2ZN, UK, graham.macdonald@nhs.net.

The Journal of the Royal College of Physicians of Edinburgh
|June 13, 2019
PubMed
Summary
This summary is machine-generated.

Malignant spinal cord compression (MSCC) is a serious cancer complication. This paper details a new pathway at Aberdeen Royal Infirmary to improve early diagnosis and patient outcomes for MSCC.

Keywords:
cauda equina compressionmalignant spinal cord compression

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Area of Science:

  • Oncology
  • Neurology
  • Medical Diagnostics

Background:

  • Malignant spinal cord compression (MSCC) is a severe oncological emergency.
  • Delayed diagnosis of MSCC can lead to irreversible neurological damage and permanent disability.
  • Effective management requires prompt recognition of symptoms and rapid diagnostic workup.

Purpose of the Study:

  • To describe the development and implementation of a streamlined diagnostic pathway for suspected malignant spinal cord compression (MSCC).
  • To improve the timeliness of diagnosis and initiation of treatment for cancer patients with MSCC.
  • To enhance collaboration between oncology, neurology, and radiology departments for MSCC management.

Main Methods:

  • Development of a multidisciplinary MSCC protocol.
  • Implementation of standardized information dissemination to clinicians and patients regarding MSCC risks.
  • Establishment of a direct referral system for urgent MSCC investigation.

Main Results:

  • The new pathway facilitated earlier detection of MSCC.
  • Improved communication and coordination among clinical teams.
  • Potential for reduced diagnostic delays and improved patient outcomes.

Conclusions:

  • A streamlined diagnostic pathway is crucial for managing malignant spinal cord compression (MSCC).
  • Early recognition and prompt investigation significantly impact patient prognosis.
  • This initiative at Aberdeen Royal Infirmary serves as a model for improving MSCC care.