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Updated: Oct 13, 2026

The Neuroblast Assay: An Assay for the Generation and Enrichment of Neuronal Progenitor Cells from Differentiating Neural Stem Cell Progeny Using Flow Cytometry
15:40

The Neuroblast Assay: An Assay for the Generation and Enrichment of Neuronal Progenitor Cells from Differentiating Neural Stem Cell Progeny Using Flow Cytometry

Published on: April 22, 2012

Differential expression of alpha-subunits of G-proteins in human neuroblastoma-derived cell clones

F J Klinz1, V C Yu, W Sadée

  • 1Department of Neuropharmacology, Max-Planck-Institut für Psychiatrie, Planegg-Martinsried, FRG.

FEBS Letters
|November 16, 1987
PubMed

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Heterotrimeric G proteins are guanine nucleotide-binding proteins. As the name suggests, heterotrimeric G proteins are composed of three subunits: alpha, beta, and gamma. They remain GDP-bound or GTP-bound inside the cells and switch between inactive/active states. The Gα subunit possesses the nucleotide-binding pocket that binds guanine nucleotides and switches between GDP or GTP-bound states. In contrast, the Gꞵ and Gγ subunits are always bound together with high affinity and are together...