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Related Experiment Video

Updated: Jan 23, 2026

C. elegans Positive Butanone Learning, Short-term, and Long-term Associative Memory Assays

C. elegans Positive Butanone Learning, Short-term, and Long-term Associative Memory Assays

Published on: March 11, 2011

Learning functions in short-term cocaine users.

Danusha Selva Kumar¹, Elysia Benedict², Olivia Wu²

¹Fordham University, 441 East Fordham Road, Dealy Hall, Bronx, NY 10458, United States of America.

Addictive Behaviors Reports

|June 14, 2019

Summary

This summary is machine-generated.

Short-term cocaine use impairs learning and cognitive functions. Cocaine users showed deficits in probabilistic category learning, verbal learning, and psychomotor skills compared to controls.

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Using Optogenetics to Reverse Neuroplasticity and Inhibit Cocaine Seeking in Rats

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Published on: October 5, 2021

Area of Science:

Neuroscience
Psychology

Background:

Cocaine use is a significant public health concern.
Understanding the cognitive impact of short-term cocaine use is crucial for developing effective interventions.

Purpose of the Study:

To investigate learning and cognitive functions in individuals with short-term cocaine use.
To compare the performance of cocaine users and non-users on various learning tasks.

Main Methods:

Seventeen active cocaine users and seventeen non-cocaine-using controls were recruited.
Participants completed tasks assessing probabilistic category learning, verbal learning, executive functions, and psychomotor functions.

Main Results:

Cocaine users performed significantly worse than controls on the Weather Prediction and List-Learning tasks.
Deficits were also observed in executive and psychomotor functions among cocaine users.

Conclusions:

Short-term cocaine use is associated with moderate impairments in probabilistic category learning, verbal learning, and psychomotor functions.
These cognitive deficits may impede learning from behavioral consequences and reduce responsiveness to cognitive-behavioral treatments.