Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Definite Integral01:29

Definite Integral

52
Consider a real-valued function defined on a closed interval. One of the fundamental objectives in calculus is to determine the area under the graph of such a function. When an exact computation is not readily available, this area can be estimated by dividing the interval into a finite number of equal subintervals. Each subinterval corresponds to a rectangle whose width is the length of the subinterval and whose height is determined by the value of the function at a selected point within that...
52
Indefinite Integrals01:25

Indefinite Integrals

61
The water inflow rate into a storage tank is not constant but increases over time. Initially, the pump delivers water at a rate of 5 L/min. However, the inflow rate increases by 2 L/min for each additional minute due to rising pressure or system adjustments. This scenario can be described mathematically by a linear function:It is necessary to integrate the inflow rate function to measure the total volume of water added to the tank over time. The total water volume V(t) is obtained by performing...
61
Integrator and Differentiator01:13

Integrator and Differentiator

1.4K
Op-amp circuits have significant applications in various fields, including automotive engineering. One such application is cruise control systems in cars, where op-amp circuits are integral for maintaining a constant speed. In these systems, op-amps function as both integrators and differentiators.
An integrator within an op-amp circuit produces an output directly proportional to the integral of the input signal. This is achieved by replacing the feedback resistor in a typical inverting...
1.4K
Integrated Healthcare System01:20

Integrated Healthcare System

2.4K
An integrated healthcare system (IHS) is a set of organizations that provides for or arranges to provide coordinated and continuous service to a defined population. The IHS takes responsibility for that particular population's health status and outcome, both clinically and fiscally. An integrated healthcare system is a well-organized, well-coordinated, and collaborative network. The integrated delivery system is a network that connects different healthcare providers to deliver organized,...
2.4K
The Integrated Rate Law: The Dependence of Concentration on Time02:39

The Integrated Rate Law: The Dependence of Concentration on Time

41.1K
While the differential rate law relates the rate and concentrations of reactants, a second form of rate law called the integrated rate law relates concentrations of reactants and time. Integrated rate laws can be used to determine the amount of reactant or product present after a period of time or to estimate the time required for a reaction to proceed to a certain extent. For example, an integrated rate law helps determine the length of time a radioactive material must be stored for its...
41.1K
Properties of Definite Integral I01:30

Properties of Definite Integral I

45
A car’s motion over time can be effectively analyzed using integral calculus, particularly through the concept of the definite integral applied to a velocity–time relationship. The definite integral describes how velocity accumulates over a specified time interval to produce total displacement. From a geometric perspective, this displacement is interpreted as the area under the velocity–time curve. Several key properties of definite integrals make it easier to analyze motion...
45

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Unravelling the local structure and magnetic dynamics of Cu-doped MnV₂O₄.

Journal of physics. Condensed matter : an Institute of Physics journal·2026
Same author

Direct Synthesis of Ultrathin Hexagonal Boron Nitride Films on Si(001).

Nano letters·2026
Same author

Optimizing Graphene Ring Modulators: A Comparative Study of Straight, Bent, and Racetrack Geometries.

Nanomaterials (Basel, Switzerland)·2025
Same author

Comparative simulation analysis of photonic ultrasound sensors based on silicon waveguides.

Scientific reports·2025
Same author

Synthesis, Characterization, and Reactivity of Aminotroponiminate-Based Difluoroboranes: A Pathway toward Bore(boro)nium Cations.

Inorganic chemistry·2025
Same author

Magnesium-Mediated Cyanosilylation and Hydroboration of Arene and N-Heteroarene Aldehydes: An Experimental and Theoretical Study.

Chemistry, an Asian journal·2025

Related Experiment Video

Updated: Jan 23, 2026

Author Spotlight: Advancing Large-Scale Neural Dynamics Through HD-MEA Technology
09:44

Author Spotlight: Advancing Large-Scale Neural Dynamics Through HD-MEA Technology

Published on: March 8, 2024

5.8K

Towards CMOS Integrated Microfluidics Using Dielectrophoretic Immobilization.

Honeyeh Matbaechi Ettehad1, Rahul Kumar Yadav2, Subhajit Guha3

  • 1IHP-Leibniz-Institut für innovative Mikroelektronik, Im Technologiepark 25, 15236 Frankfurt/Oder, Germany. matbaechi@ihp-microelectronics.com.

Biosensors
|June 15, 2019
PubMed
Summary
This summary is machine-generated.

Dielectrophoresis (DEP) enables noninvasive manipulation of biological particles using interdigitated electrodes (IDEs) in microfluidic systems. Finite element simulations optimize IDE design for CMOS-integrated devices, crucial for point-of-care diagnostics.

Keywords:
CMOS biosensorbiomoleculesdielectrophoretic immobilizationlab-on-chipmicrofluidic

More Related Videos

Immobilization of Live Caenorhabditis elegans Individuals Using an Ultra-thin Polydimethylsiloxane Microfluidic Chip with Water Retention
04:55

Immobilization of Live Caenorhabditis elegans Individuals Using an Ultra-thin Polydimethylsiloxane Microfluidic Chip with Water Retention

Published on: March 19, 2019

8.3K
Traction Microscopy Integrated with Microfluidics for Chemotactic Collective Migration
10:53

Traction Microscopy Integrated with Microfluidics for Chemotactic Collective Migration

Published on: October 13, 2019

7.4K

Related Experiment Videos

Last Updated: Jan 23, 2026

Author Spotlight: Advancing Large-Scale Neural Dynamics Through HD-MEA Technology
09:44

Author Spotlight: Advancing Large-Scale Neural Dynamics Through HD-MEA Technology

Published on: March 8, 2024

5.8K
Immobilization of Live Caenorhabditis elegans Individuals Using an Ultra-thin Polydimethylsiloxane Microfluidic Chip with Water Retention
04:55

Immobilization of Live Caenorhabditis elegans Individuals Using an Ultra-thin Polydimethylsiloxane Microfluidic Chip with Water Retention

Published on: March 19, 2019

8.3K
Traction Microscopy Integrated with Microfluidics for Chemotactic Collective Migration
10:53

Traction Microscopy Integrated with Microfluidics for Chemotactic Collective Migration

Published on: October 13, 2019

7.4K

Area of Science:

  • Biomedical Engineering
  • Microfluidics
  • Nanotechnology

Background:

  • Dielectrophoresis (DEP) is a non-destructive technique for manipulating biological particles.
  • Miniaturized platforms are essential for point-of-care medical diagnostics.
  • Complementary metal-oxide-semiconductor (CMOS) technology offers advanced planar fabrication for biosensors.

Purpose of the Study:

  • To investigate dielectrophoretic immobilization of micron and submicron particles using interdigitated electrode (IDE) arrays.
  • To optimize IDE design through finite element simulations for CMOS-integrated microfluidics.
  • To analyze the influence of DEP parameters and fluid dynamics on particle manipulation.

Main Methods:

  • Finite element simulations were employed to model DEP force actuation and IDE geometry.
  • Simulations were performed using non-biological particles in a silicon microfluidic channel.
  • The impact of AC field parameters (voltage, frequency), flow velocity, and IDE geometry was investigated.

Main Results:

  • The study established the feasibility of using CMOS-compatible IDEs for dielectrophoretic particle manipulation.
  • Finite element analysis provided insights into optimizing IDE design for efficient particle trapping.
  • Key parameters influencing DEP force and particle behavior in microfluidic channels were identified.

Conclusions:

  • Optimized IDE design is critical for effective dielectrophoretic immobilization in microfluidic systems.
  • CMOS-compatible IDEs integrated into microfluidic channels show promise for advanced diagnostics.
  • Further research will detail the sensing and detection mechanisms for integrated systems.