Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Intrinsically Disordered Proteins02:18

Intrinsically Disordered Proteins

19.3K
Intrinsically disordered proteins are a group of proteins that do not fold into specific three-dimensional structures. Their structural flexibility allows them to complement ordered proteins to perform functions that are inaccessible to rigid structures. They are more common in eukaryotes than prokaryotes and may either be exclusively intrinsically disordered or hybrid proteins, consisting of a mix of ordered and disordered regions. The absence of a rigid structure in these proteins can be...
19.3K
Multiple Allele Traits01:49

Multiple Allele Traits

38.0K
The Concept of Multiple Allelism
38.0K
Other Disorders of Digestive System01:30

Other Disorders of Digestive System

1.4K
The gastrointestinal tract is susceptible to various disorders. If the lower esophageal sphincter is damaged, stomach acid can flow back into the esophagus, causing irritation and inflammation of the lining. This condition is called gastroesophageal reflux disease (known as heartburn) and may cause chest pain and difficulty swallowing. In the stomach, prolonged use of nonsteroidal anti-inflammatory drugs like aspirin, chronic alcohol consumption, bacterial infections such as Helicobacter...
1.4K
Disorders of Erythrocytes01:27

Disorders of Erythrocytes

2.1K
Disorders of erythrocytes, or red blood cells (RBCs), include a range of conditions affecting their number, shape, or function.
Erythrocyte disorders can be broadly categorized into two main types: anemic and polycythemic conditions.
A low oxygen-carrying capacity of the blood due to the loss, lower production, or destruction of erythrocytes is termed anemia. Hemorrhagic anemia, for example, occurs when bleeding from an external wound or internal ulcer reduces erythrocyte counts.
On the other...
2.1K
Disorders of Leukocytes01:27

Disorders of Leukocytes

1.8K
Leukocyte disorders can lead to either leukopenia, characterized by an abnormally low leukocyte count, or leukocytosis, marked by a very high leukocyte number.
Leukopenia may result from bone marrow disorders, autoimmune diseases, and infectious diseases. For example, conditions such as multiple myeloma and aplastic anemia can impair the bone marrow's ability to produce adequate leukocytes. Similarly, autoimmune diseases like lupus and viral infections such as HIV can prompt the immune...
1.8K
Bone Disorders01:29

Bone Disorders

5.1K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
5.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Evaluating LLM diagnostic reasoning: a new frontier for clinical AI assessment.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·2026
Same author

Web-based family-reported outcomes to assess family functioning in multiple sclerosis: an Italian multicenter digital survey.

International journal of medical informatics·2026
Same author

Clinical telemonitoring and telerehabilitation of cognition in rare neurological diseases: a scoping review.

Journal of neurology·2026
Same author

Refining neuropsychological assessment strategies in multiple sclerosis: insights from long-term cognitive trajectories.

Journal of neurology·2026
Same author

Accelerating digital innovation in clinical neuropsychology: simulation approach to support medical device certification.

Frontiers in digital health·2026
Same author

Abuse in individuals with multiple sclerosis: the SocialMS Italian study.

Multiple sclerosis and related disorders·2026
Same journal

The dual role of mTOR in multiple sclerosis pathophysiology: a systematic review.

Journal of neurology·2026
Same journal

Brain-first versus body-first Parkinson's disease: Differential findings on pupillary, brainstem and vagus sonography.

Journal of neurology·2026
Same journal

Spontaneous intracranial hypotension due to pelvic cerebrospinal fluid leak.

Journal of neurology·2026
Same journal

Morbidity and medication use preceding a diagnosis of late-onset Alzheimer's disease: a Danish nationwide study.

Journal of neurology·2026
Same journal

Comorbid autoimmune disease in stiff-person syndrome spectrum disorder: a systematic review and meta-analysis.

Journal of neurology·2026
Same journal

Tetrahydrocannabinol/cannabidiol in the treatment of restless legs syndrome.

Journal of neurology·2026
See all related articles

Related Experiment Video

Updated: Jan 23, 2026

A Multiple Integrated Social Stress Model for Psychiatric Disorders in Female C57BL/6J Mice
06:15

A Multiple Integrated Social Stress Model for Psychiatric Disorders in Female C57BL/6J Mice

Published on: July 15, 2025

1.2K

Psychiatric disorders in multiple sclerosis.

Maddalena Sparaco1, Luigi Lavorgna1, Simona Bonavita2,3,4

  • 1Department of Advanced Medical and Surgical Sciences, University of Campania "Luigi Vanvitelli", Piazza Miraglia, 2, 80138, Naples, Italy.

Journal of Neurology
|June 15, 2019
PubMed
Summary
This summary is machine-generated.

Psychiatric symptoms are common in multiple sclerosis (MS) and impact quality of life. This review covers epidemiological, clinical, and radiological aspects of psychiatric syndromes in MS patients.

Keywords:
Magnetic resonance imagingMultiple sclerosisPsychiatric disordersQuality of lifeSelf-report scale

More Related Videos

Comprehensive Autopsy Program for Individuals with Multiple Sclerosis
09:41

Comprehensive Autopsy Program for Individuals with Multiple Sclerosis

Published on: July 19, 2019

12.0K
The Multiple Sclerosis Performance Test MSPT: An iPad-Based Disability Assessment Tool
11:35

The Multiple Sclerosis Performance Test MSPT: An iPad-Based Disability Assessment Tool

Published on: June 30, 2014

58.7K

Related Experiment Videos

Last Updated: Jan 23, 2026

A Multiple Integrated Social Stress Model for Psychiatric Disorders in Female C57BL/6J Mice
06:15

A Multiple Integrated Social Stress Model for Psychiatric Disorders in Female C57BL/6J Mice

Published on: July 15, 2025

1.2K
Comprehensive Autopsy Program for Individuals with Multiple Sclerosis
09:41

Comprehensive Autopsy Program for Individuals with Multiple Sclerosis

Published on: July 19, 2019

12.0K
The Multiple Sclerosis Performance Test MSPT: An iPad-Based Disability Assessment Tool
11:35

The Multiple Sclerosis Performance Test MSPT: An iPad-Based Disability Assessment Tool

Published on: June 30, 2014

58.7K

Area of Science:

  • Neurology
  • Psychiatry
  • Neuroimmunology

Background:

  • Multiple sclerosis (MS) presents a wide array of symptoms affecting all functional systems.
  • Psychiatric symptoms are prevalent in people with MS (pwMS), significantly impacting their quality of life.
  • Key psychiatric disturbances in MS include depressive, bipolar, anxiety, schizophrenic, and obsessive-compulsive syndromes.

Purpose of the Study:

  • To review the epidemiological and clinical aspects of psychiatric syndromes (PS) in MS.
  • To describe self-report diagnostic scales for PS in MS.
  • To explore radiological correlates of PS in MS and compare them with primary psychiatric disorders (PD).

Main Methods:

  • Comprehensive literature search of original articles and reviews.
  • Databases searched include PubMed and Scopus.
  • Timeframe for literature search: 1959 to 2019.

Main Results:

  • Epidemiological and clinical data on PS in MS were compiled.
  • Self-report diagnostic scales for PS in MS were detailed.
  • Radiological findings in MS-PS and PD were analyzed, noting shared features like gray matter atrophy and white matter abnormalities.

Conclusions:

  • Psychiatric syndromes are a significant concern for people with MS.
  • Radiological similarities between MS and primary psychiatric disorders may explain increased PD prevalence in MS.
  • Understanding these connections is crucial for comprehensive MS care.