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External Ca2+-dependent Ca2+ release in directly stimulated diaphragm muscles of mice
1Department of Chemical Pharmacology, Faculty of Pharmaceutical Science, Toyama Medical and Pharmaceutical University, Japan.
Japanese Journal of Pharmacology
|August 1, 1987
Abstract:
Intracellular Ca2+ release in directly stimulated diaphragm muscles of mice was found to be dependent on external Ca2+, using the intracellular Ca2+ aequorin luminescence transient technique. The Ca2+ mobilization into the cells may operate via a voltage- and external Ca2+-dependent mechanism, and via a caffeine- and external Ca2+-independent one, from the Ca2+ pools in plasma membranes or in the terminal cisternae of sarcoplasmic reticulum.