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Sonographic Appearances of Liposarcoma: Correlations with Pathologic Subtypes.
Naoko Shimamori1, Tomonori Kishino2, Takeshi Morii3
1Department of Clinical Laboratory, Kyorin University Hospital, Tokyo, Japan.
Ultrasound in Medicine & Biology
|June 17, 2019
Summary
This study clarifies sonographic appearances for liposarcoma subtypes. Different echogenicity and vascularity patterns distinguish well-differentiated, myxoid, dedifferentiated, and pleomorphic liposarcomas.
Area of Science:
- Radiology
- Oncology
- Pathology
Background:
- Liposarcoma is the second most common malignant soft-tissue tumor.
- Four subtypes exist: well-differentiated, myxoid, dedifferentiated, and pleomorphic.
- Sonographic features of these subtypes require further investigation.
Purpose of the Study:
- To elucidate the sonographic appearances of each liposarcoma subtype.
- To correlate sonographic findings with histopathology.
- To improve diagnostic accuracy for liposarcoma subtypes using ultrasound.
Main Methods:
- Retrospective analysis of 35 liposarcoma cases.
- Inclusion of 21 well-differentiated, 6 myxoid, 6 dedifferentiated, and 2 pleomorphic liposarcomas.
- Detailed assessment of sonographic characteristics including echogenicity and vascularity.
Main Results:
- Well-differentiated liposarcoma: isoechogenicity, tiny hyperechoic lines, hypovascularity.
- Myxoid liposarcoma: low echogenicity, anechoic areas, moderate vascularity.
- Dedifferentiated liposarcoma: biphasic pattern, hypervascularity.
- Pleomorphic liposarcoma: gyrus-like hyperechoic/hypoechoic mixture.
Conclusions:
- Distinct sonographic patterns characterize the four liposarcoma subtypes.
- Ultrasound can differentiate liposarcoma subtypes based on specific imaging features.
- Sonography offers valuable insights into liposarcoma histopathology.
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