Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Intelligence01:27

Intelligence

8.5K
The term "intelligence" is complex because it refers to both behavior and individuals, and its interpretation varies across cultures. European Americans tend to link intelligence with reasoning and cognitive skills, while in Kenya, it is tied to responsible participation in family and social life. In Uganda, intelligence is seen as the ability to know the right actions and carry them out effectively, while the Iatmul people of Papua New Guinea associate it with the capacity to remember...
8.5K
Internal Energy02:00

Internal Energy

36.6K
The total of all possible kinds of energy present in a substance is called the internal energy (U), sometimes symbolized as E. Suppose a system with initial internal energy, Uinitial, undergoes a change in energy (transfer of work or heat), and the final internal energy of the system is Ufinal. Change in internal energy equals the difference between Ufinal and Uinitial.
36.6K
Internal Energy01:29

Internal Energy

6.9K
The internal energy of a thermodynamic system is the sum of the kinetic and potential energies of all the molecules or entities in the system. The kinetic energy of an individual molecule includes contributions due to its rotation and vibration, as well as its translational energy. The potential energy is associated only with the interactions between one molecule and the other molecules of the system. Neither the system's location nor its motion is of any consequence as far as the internal...
6.9K
Internal Receptors01:31

Internal Receptors

74.3K
Many cellular signals are hydrophilic and therefore cannot pass through the plasma membrane. However, small or hydrophobic signaling molecules can cross the hydrophobic core of the plasma membrane and bind to internal, or intracellular, receptors that reside within the cell. Many mammalian steroid hormones use this mechanism of cell signaling, as does nitric oxide (NO) gas.
74.3K
Measures of Intelligence01:29

Measures of Intelligence

8.4K
Psychologists measure intelligence by using standardized tests that produce a score known as the intelligence quotient or IQ. To understand IQ tests, it's important to recognize the key principles behind their construction: validity, reliability, and standardization.
Validity refers to how well a test measures what it claims to measure. An intelligence test should accurately assess intelligence rather than another characteristic, like anxiety. Criterion validity is one way to evaluate this;...
8.4K
Multiple Intelligences Theory01:20

Multiple Intelligences Theory

8.9K
Howard Gardner's theory of Multiple Intelligence proposes that there are nine distinct types of intelligence, each reflecting different ways of interacting with the world. Introduced in 1983 and expanded in subsequent years, Gardner's framework challenges the traditional notion of a single, generalized intelligence.
8.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Global seroprevalence of neutralizing antibodies against adeno-associated virus serotypes used for human gene therapies.

Molecular therapy. Methods & clinical development·2024
Same author

Using large language models for safety-related table summarization in clinical study reports.

JAMIA open·2024
Same author

CATO: The Clone Alignment Tool.

PloS one·2016
Same author

miRNA Alterations Modify Kinase Activation In The IGF-1 Pathway And Correlate With Colorectal Cancer Stage And Progression In Patients.

Journal of Cancer·2011
Same author

ERK activation by GM-CSF reduces effectiveness of p38 inhibitor on inhibiting TNFalpha release.

International immunopharmacology·2010
Same author

Cellular imaging predictions of clinical drug-induced liver injury.

Toxicological sciences : an official journal of the Society of Toxicology·2008

Related Experiment Video

Updated: Jan 23, 2026

Author Spotlight: Addressing Technical and Subjective Challenges in Measuring Classroom Attention
06:37

Author Spotlight: Addressing Technical and Subjective Challenges in Measuring Classroom Attention

Published on: December 15, 2023

5.3K

Artificial Intelligence for Pharma: Time for Internal Investment.

Peter V Henstock1

  • 1Pfizer Digital, Pfizer Inc., Andover, MA, USA.

Trends in Pharmacological Sciences
|June 18, 2019
PubMed
Summary

This article explores how pharmaceutical companies can better utilize artificial intelligence to improve drug discovery and business operations. It emphasizes that success depends on prioritizing high-quality data management and hiring internal experts who can apply machine learning to specific company challenges.

Keywords:
AIdata sciencemachine learningpharmamachine learningdrug discoverydigital transformationcorporate strategy

Frequently Asked Questions

More Related Videos

Automation of the Micronucleus Assay Using Imaging Flow Cytometry and Artificial Intelligence
09:11

Automation of the Micronucleus Assay Using Imaging Flow Cytometry and Artificial Intelligence

Published on: January 27, 2023

2.7K
Introduction of an Integrated Pathology Image Management, Artificial Intelligence, and Reporting System
05:33

Introduction of an Integrated Pathology Image Management, Artificial Intelligence, and Reporting System

Published on: July 11, 2025

840

Related Experiment Videos

Last Updated: Jan 23, 2026

Author Spotlight: Addressing Technical and Subjective Challenges in Measuring Classroom Attention
06:37

Author Spotlight: Addressing Technical and Subjective Challenges in Measuring Classroom Attention

Published on: December 15, 2023

5.3K
Automation of the Micronucleus Assay Using Imaging Flow Cytometry and Artificial Intelligence
09:11

Automation of the Micronucleus Assay Using Imaging Flow Cytometry and Artificial Intelligence

Published on: January 27, 2023

2.7K
Introduction of an Integrated Pathology Image Management, Artificial Intelligence, and Reporting System
05:33

Introduction of an Integrated Pathology Image Management, Artificial Intelligence, and Reporting System

Published on: July 11, 2025

840

Area of Science:

  • Artificial intelligence applications in pharmaceutical research
  • Data management strategies within corporate drug development

Background:

No prior work had resolved how pharmaceutical firms should best integrate advanced computational tools into their existing workflows. It was already known that machine learning models have reached performance levels comparable to human experts. That uncertainty drove interest in whether external partnerships or internal development would yield superior long-term results. Prior research has shown that data quality remains a significant bottleneck for many large-scale digital initiatives. This gap motivated a closer look at the organizational requirements for successful technology adoption. Many companies struggle to bridge the divide between raw information and actionable business insights. The industry currently faces pressure to accelerate timelines while simultaneously reducing the high costs of drug development. These factors highlight the need for a strategic shift toward building internal capabilities rather than relying solely on third-party vendors.

Purpose Of The Study:

The aim of this article is to evaluate how pharmaceutical organizations can effectively integrate advanced computational tools to improve their business outcomes. The researchers address the challenge of transitioning from traditional development methods to modern, data-driven strategies. This work explores the motivation behind the current push for digital transformation in the healthcare sector. The authors investigate why some firms struggle to derive value from their existing information repositories. The study seeks to clarify the role of human expertise in managing complex automated systems. By identifying the barriers to adoption, the team provides a roadmap for sustainable technological growth. The researchers intend to highlight the necessity of prioritizing internal skill sets over external partnerships. This analysis serves to guide leadership in making informed decisions regarding long-term investments in digital infrastructure.

Main Methods:

Review approach involved analyzing current trends in digital transformation within the healthcare sector. The authors evaluated organizational structures that successfully integrate advanced computational models into daily operations. This assessment focused on the relationship between human expertise and automated decision-making systems. The study examined how firms manage proprietary information to support machine learning initiatives. Researchers compared the efficacy of internal development versus external outsourcing for long-term technological growth. The investigation synthesized evidence regarding the requirements for building sustainable digital capabilities. The team identified key barriers that prevent companies from fully utilizing their existing data assets. This systematic review provided a framework for understanding how leadership can foster a culture of innovation through targeted investment.

Main Results:

Key findings from the literature suggest that machine learning capabilities have reached performance levels equivalent to human specialists. The authors report that these tools offer significant potential for enhancing decision-making across the entire drug development pipeline. Evidence indicates that the most successful firms prioritize the creation of internal teams over reliance on outside vendors. The review highlights that high-quality data management is a prerequisite for achieving meaningful results with automated systems. Findings show that companies often fail to extract value from their own information due to poor organizational alignment. The data suggests that internal experts are better positioned to tackle proprietary business problems than external consultants. The authors note that the rapid improvement of these technologies necessitates a proactive approach to talent acquisition. Results demonstrate that integrating digital skills directly into the workforce is a primary driver of competitive advantage.

Conclusions:

The authors suggest that internal investment in specialized staff remains the most effective path for long-term innovation. They argue that corporate data assets represent a unique competitive advantage when processed correctly. Synthesis and implications indicate that companies must prioritize infrastructure to support complex computational workflows. The researchers propose that business leaders should view digital talent as a primary driver of future success. Their analysis implies that relying on external solutions may limit a firm's ability to solve specific, proprietary problems. The authors conclude that integrating technical expertise directly into the organization fosters better decision-making processes. They maintain that the combination of high-quality data and skilled personnel creates sustainable value. The review suggests that the transition toward internal digital mastery is necessary for maintaining a competitive edge in the modern pharmaceutical landscape.

The authors propose that internal teams leverage proprietary corporate data to address specific business challenges. This approach allows firms to move beyond generic external models and develop tailored solutions that directly improve drug discovery and operational decision-making processes.

Internal talent refers to specialized staff hired directly by the company to build and maintain machine learning systems. These experts are responsible for transforming raw information into actionable insights, which distinguishes them from external consultants who may lack deep institutional knowledge.

Data management is necessary because high-quality, organized information serves as the foundation for all machine learning models. Without clean and accessible datasets, even the most advanced algorithms fail to produce reliable results, making infrastructure investment a prerequisite for success.

Corporate data acts as the primary fuel for training custom algorithms. By utilizing this proprietary information, companies can create unique models that address their specific drug development hurdles, providing a distinct advantage over competitors who rely on public or generic datasets.

The researchers measure success through the ability of internal teams to solve complex business problems. This phenomenon involves moving from simple data collection to the active application of predictive models that inform strategic choices throughout the drug development lifecycle.

The authors imply that firms failing to invest in internal capabilities risk falling behind in the global market. They suggest that the shift toward self-sufficiency in digital technologies is a long-term requirement for companies aiming to sustain innovation and improve patient outcomes.