Related Experiment Video

Updated: Jan 23, 2026

Author Spotlight: Automated Lifespan Monitoring – Discovering Aging Dynamics with the Lifespan Machine
08:53

Author Spotlight: Automated Lifespan Monitoring – Discovering Aging Dynamics with the Lifespan Machine

Published on: January 26, 2024

1.6K

Extracellular Vesicle-Contained eNAMPT Delays Aging and Extends Lifespan in Mice

Mitsukuni Yoshida1, Akiko Satoh2, Jonathan B Lin3

  • 1Department of Developmental Biology, Washington University School of Medicine, St. Louis, MO 63110, USA; MD-PhD Program, Washington University School of Medicine, St. Louis, MO 63110, USA.

Cell Metabolism
|June 18, 2019
PubMed

Keywords:
EVNAD+adipose tissueagingeNAMPTexosomeextracellular vesiclehypothalamuslongevitymetabolism

More Related Videos

Studying Age-dependent Genomic Instability using the S. cerevisiae Chronological Lifespan Model08:46

Studying Age-dependent Genomic Instability using the S. cerevisiae Chronological Lifespan Model

Published on: September 29, 2011

16.0K
Setting a Successful Sorting for Extracellular Vesicle Isolation08:37

Setting a Successful Sorting for Extracellular Vesicle Isolation

Published on: October 11, 2024

1.6K

Related Concept Videos

Aging01:26

Aging

Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
636
The Extracellular Matrix01:42

The Extracellular Matrix

Overview
88.3K
The Extracellular Matrix01:29

The Extracellular Matrix

Overview
In order to maintain tissue organization, many animal cells are surrounded by structural molecules that make up the extracellular matrix (ECM). Together, the molecules in the ECM maintain the structural integrity of tissue as well as the remarkable specific properties of certain tissues.
Composition of the Extracellular Matrix
The extracellular matrix (ECM) is commonly composed of ground substance, a gel-like fluid, fibrous components, and many structurally and functionally diverse...
12.0K
The Effect of Aging on Tissues01:19

The Effect of Aging on Tissues

Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
3.4K
Gravitational Potential Energy for Extended Objects01:07

Gravitational Potential Energy for Extended Objects

Consider a system comprising several point masses. The coordinates of the center of mass for this system can be expressed as the summation of the product of each mass and its position vector divided by the total mass:
1.9K
Changes in the Appendicular Skeleton with Age01:09

Changes in the Appendicular Skeleton with Age

The upper and lower limb initially develops as a small bulge called a limb bud, which appears on the lateral side of the early embryo. The upper limb bud appears near the end of the fourth week of development, with the lower limb bud appearing shortly after.
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...
3.4K