Related Experiment Video
Updated: Jan 23, 2026
07:57
An Experimental Human DIEP Flap Model to Investigate Preservation Strategies for Vascularized Composite Allografts and Free Flaps
Published on: December 5, 2025
225
Composite Nasoseptal Flap for Palate Reconstruction.
Shekhar K Gadkaree1, Allen L Feng1, Jeffery D Sharon2
1Department of Otolaryngology, Harvard Medical School, Massachusetts Eye and Ear, Boston, MA.
The Journal of Craniofacial Surgery
|June 18, 2019
Summary
The nasoseptal flap is a viable option for reconstructing hard palate defects, offering structural integrity and minimal donor site morbidity. This technique can reliably repair defects up to 2.5 cm.
Area of Science:
- Plastic Surgery
- Otolaryngology
- Head and Neck Surgery
Background:
- Palatal fistulae pose significant reconstructive challenges, often complicated by prior treatments like radiotherapy or surgery.
- Existing reconstructive options may be limited by previous interventions.
Purpose of the Study:
- To evaluate the utility of the nasoseptal flap for palatal fistula repair.
- To assess the feasibility of harvesting a composite nasoseptal flap including septal cartilage and contralateral mucoperichondrium.
Main Methods:
- A prospective study involving 5 cadaver dissections.
- Primary outcomes included the anterior reach of the flap and the size of defect it could reconstruct.
Main Results:
- Composite nasoseptal flaps were successfully harvested, providing structural integrity.
- The flap's maximum anterior reach was 2.0 cm from the anterior nasal spine.
- Defects up to 2.5 cm could be reliably reconstructed.
Conclusions:
- The nasoseptal flap is a viable regional option for hard palate defect reconstruction.
- Further clinical trials are needed to assess long-term outcomes.
Related Concept Videos
03:35Classifying Matter by Composition
89.9K
Matter: Pure Substances and Mixtures
According to its composition, the matter can be classified into two broad categories — pure substances and mixtures.
A pure substance is a form of matter that has a constant composition throughout with uniform properties. For example, any sample of sucrose has the same composition and same physical properties, such as melting point, color, and sweetness, regardless of the source from which it is isolated.
A mixture is composed of two or...
According to its composition, the matter can be classified into two broad categories — pure substances and mixtures.
A pure substance is a form of matter that has a constant composition throughout with uniform properties. For example, any sample of sucrose has the same composition and same physical properties, such as melting point, color, and sweetness, regardless of the source from which it is isolated.
A mixture is composed of two or...
89.9K
01:22Composition of Blood
11.6K
The blood in our bodies comprises three major components: blood plasma, formed elements, and the extracellular matrix. Blood plasma is a yellowish fluid that constitutes 55% of the total blood volume. It is primarily made up of water and essential substances such as electrolytes and proteins. Blood plasma serves as a medium for transporting blood cells and also contains nutrients, enzymes, hormones, antibodies, and gases.
Formed elements constitute the remaining 45% of the blood volume. These...
Formed elements constitute the remaining 45% of the blood volume. These...
11.6K
00:55Composite Bodies
1.4K
A composite body is a body made up of multiple parts, connected to form a larger, unified object. Each part has its own weight and center of gravity, which must be considered to determine the center of gravity of the composite body. In cases where the density or specific weight is constant, the center of gravity coincides with the centroid.
Composite bodies have widespread applications in mechanical engineering, from automobiles to aircraft to rockets. For example, an automobile wheel comprises...
Composite bodies have widespread applications in mechanical engineering, from automobiles to aircraft to rockets. For example, an automobile wheel comprises...
1.4K
01:10Reconstruction of Signal using Interpolation
704
Signal processing techniques are essential for accurately converting continuous signals to digital formats and vice versa. When a continuous signal is sampled with a period T, the resulting sampled signal exhibits replicas of the original spectrum in the frequency domain, spaced at intervals equal to the sampling frequency. To handle this sampled signal, a zero-order hold method can be applied, which creates a piecewise constant signal by retaining each sample's value until the next...
704
01:29Composition of Body Fluids
2.4K
Water functions as a solvent accommodating various solutes, which can be categorized under electrolytes and non-electrolytes. Non-electrolytes are usually held together by covalent bonds, restricting them from dissociating in solution, thereby leading to a lack of electrically charged components upon dissolving in water. They are predominantly organic molecules, such as glucose, creatinine, and urea. Electrolytes, on the other hand, are compounds that can break down into ions in water.
2.4K
01:24Composition of Blood Plasma
8.0K
Blood plasma is a fluid that contains approximately 92% water and 8% solutes. The solutes include various types of proteins, which constitute about 7% of the total solutes in the plasma. The high-molecular-weight proteins—albumins, globulins, and fibrinogen—are essential to plasma function. Albumins, making up about 60% of the plasma proteins, maintain the osmotic balance within blood vessels by preventing excessive water leakage. Additionally, albumins serve as carrier proteins,...
8.0K