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Association between chronic rhinosinusitis and osteoporosis: a case-control study using a national sample cohort
Hyo Geun Choi1, Il Gyu Kong1,2
1Department of Otorhinolaryngology-Head and Neck Surgery, Hallym University College of Medicine, Anyang, Korea.
International Forum of Allergy & Rhinology
|June 18, 2019
Summary
Osteoporosis patients show a higher incidence of chronic rhinosinusitis (CRS). This study found a 47% increased odds of CRS in individuals with osteoporosis, consistent across all demographics.
Area of Science:
- Otorhinolaryngology
- Bone Metabolism & Endocrinology
Background:
- Chronic rhinosinusitis (CRS) and osteoporosis are prevalent conditions.
- Understanding comorbidities is crucial for comprehensive patient care.
Purpose of the Study:
- To investigate the association between chronic rhinosinusitis (CRS) and osteoporosis.
- To clarify this relationship within the Korean population.
Main Methods:
- A population-based cohort study (2002-2013) using Korean National Health Insurance data.
- Matched 68,459 osteoporosis patients with 68,459 controls based on demographics and comorbidities.
- Conditional logistic regression analyzed CRS history in relation to osteoporosis, calculating adjusted odds ratios (ORs) and 95% confidence intervals (CIs).
Main Results:
- The prevalence of CRS was significantly higher in the osteoporosis group (3.0%) compared to the control group (2.0%) (p < 0.001).
- Osteoporosis was associated with a 1.47-fold increased adjusted odds of CRS (95% CI, 1.37-1.58; p < 0.001).
- Subgroup analyses confirmed consistent findings across age and sex groups.
Conclusions:
- Osteoporosis is independently associated with an increased risk of chronic rhinosinusitis.
- This association was robust and consistent across various demographic subgroups.
Keywords:
chronic rhinosinusitisepidemiologynested case-control studiesosteoporosisrhinosinusitissinusitisMore Related Videos
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