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Updated: Jan 23, 2026

Microsurgical Clip Obliteration of Middle Cerebral Aneurysm Using Intraoperative Flow Assessment
Published on: September 25, 2009
Brain Bypass Surgery for Complex Middle Cerebral Artery Aneurysms: Evolving Techniques, Results, and Lessons Learned
Sabareesh K Natarajan1, Qazi Zeeshan2, Basavaraj V Ghodke3
1Department of Neurosurgery, University of Massachusetts Medical School, Worcester, Massachusetts, USA.
Cerebral revascularization effectively treats middle cerebral artery (MCA) aneurysms, achieving high occlusion rates with patent bypasses. This technique offers a safe adjunct for complex MCA aneurysms, improving patient outcomes.
Area of Science:
- Neurosurgery
- Vascular Neurology
- Cerebrovascular Surgery
Background:
- Middle cerebral artery (MCA) aneurysms often require complex treatment strategies.
- Achieving complete aneurysm occlusion while preserving flow through critical MCA branches can be challenging.
- Adjunctive cerebral revascularization is sometimes necessary for successful MCA aneurysm treatment.
Purpose of the Study:
- To analyze the safety and efficacy of cerebral revascularization as an adjunct procedure for treating middle cerebral artery (MCA) aneurysms.
- To evaluate the long-term patency of bypass grafts and the rates of aneurysm occlusion.
- To assess clinical outcomes and functional status following revascularization for MCA aneurysms.
Main Methods:
- A consecutive series of 42 patients with 43 MCA aneurysms underwent 52 bypass procedures over 13 years.
- Procedures included various intracranial and extracranial bypass techniques, such as STA-MCA anastomosis and radial artery grafts.
- Aneurysm locations ranged from the M1 trunk to M2 segments and beyond.
Main Results:
- 98% of bypasses remained patent at long-term follow-up, with complete occlusion of all 43 aneurysms.
- Six patients (14%) experienced treatment-related strokes.
- At follow-up, 73.8% of patients improved functionally (modified Rankin score 0-2).
Conclusions:
- Cerebral revascularization is a safe and effective adjunct for treating complex MCA aneurysms.
- The procedure facilitates complete aneurysm occlusion while maintaining essential cerebral blood flow.
- This study provides valuable insights from the learning curve associated with these advanced techniques.
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