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Taurolidine as adjuvant treatment of relapsing peritonitis in peritoneal dialysis patients

Kamila Klimek1, Nuria Aresté Fosalba1, Miguel Ángel Ramírez López1

  • 1Servicio de Nefrología, Hospital Universitario Virgen Macarena, Sevilla, España.

Nefrologia
|June 19, 2019
PubMed

Insights

Taurolidine shows promise in treating relapsing peritonitis in peritoneal dialysis patients by preventing catheter-related infections. While effective against Staphylococcus epidermidis, it was less successful with Staphylococcus aureus, necessitating catheter removal in one case.

Area of Science:

  • Nephrology
  • Infectious Diseases
  • Medical Devices

Background:

  • Relapsing peritonitis is a major complication in peritoneal dialysis (PD), often linked to catheter biofilm formation.
  • Current management typically involves catheter removal, disrupting PD therapy.
  • Taurolidine, known for antimicrobial properties, has been used in other catheter types but not extensively studied in PD.
Keywords:
BiofilmDiálisis peritonealPeritoneal dialysisPeritonitisTaurolidinaTaurolidine

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