Related Experiment Video
Updated: Jan 23, 2026
13:42
Clinical Examination Protocol to Detect Atypical and Classical Scrapie in Sheep
Published on: January 19, 2014
14.0K
[Atypical localization of a glomus tumor]
C Doutrelon1, P Duhamel2, A Mlynski3
1Service de médecine interne et rhumatologie, HIA Percy, avenue Henri-Barbusse, 92140 Clamart, France.
Journal De Medecine Vasculaire
|June 20, 2019
Summary
Glomous tumors, typically found in fingers, can occur elsewhere. This case highlights a supra-patellar glomous tumor causing pain and limp, successfully treated with surgery.
Area of Science:
- Orthopedics
- Oncology
- Radiology
Background:
- Glomous tumors are rare, benign neoplasms.
- Most commonly affect the digits, but atypical locations are documented.
- Supra-patellar localization can mimic other knee pathologies.
Observation:
- A patient presented with a supra-patellar glomous tumor causing a significant pain-induced limp.
- Magnetic resonance imaging (MRI) was instrumental in confirming the diagnosis of this atypical glomous tumor.
Findings:
- Complete surgical resection of the supra-patellar glomous tumor was performed.
- The patient experienced a total resolution of pain following the surgical intervention.
Implications:
- Atypical glomous tumors can be overlooked, leading to delayed or incorrect diagnoses.
- Early diagnosis and complete surgical excision are effective treatments for glomous tumors, even in unusual sites.
Related Concept Videos
01:21Antipsychotic Drugs: Typical and Atypical Agents
786
Antipsychotic drugs are classified into first-generation (typical) drugs including phenothiazines; and second-generation (atypical) drugs. Chlorpromazine hydrochloride (Thorazine), a phenothiazine derivative, broadly impacts the central, autonomic, and endocrine systems. This drug, along with typical agents like haloperidol (Haldol), primarily works by antagonizing D2 receptors, thus reducing dopaminergic neurotransmission. However, typical antipsychotics can cause side effects such as sedation...
786
01:22Local Attraction
370
Local attraction refers to disturbances in compass readings caused by magnetic influences from nearby objects such as metal fences, buried pipes, vehicles, buildings, power lines, or natural iron ore deposits. Small items like wristwatches, steel tools, or belt buckles can also interfere with the compass by creating local magnetic fields that distort the Earth's natural magnetic field. These distortions lead to inaccurate readings, posing navigation and land surveying challenges.Local...
370
01:13Local Anesthetics: Pharmacokinetics
1.2K
The potency and duration of action of local anesthetics (LAs) are determined by their pharmacokinetics. Pharmacokinetics describes how LAs are absorbed, distributed, metabolized, and eliminated from the body. When administered to the vascular tissues, LAs are quickly absorbed and enter the systemic circulation, reducing their localized effects. Adding vasoconstrictors such as epinephrine to LAs reduces their absorption into the systemic circulation, making them clinically effective. The...
1.2K
01:23Local Anesthetics: Mechanism of Action
3.3K
Local anesthetics (LAs) block sensory and motor impulses by inhibiting the sodium channels on the nerve cell membranes. This induces temporary loss of sensation, relieving pain in a specific body area.
Local anesthetics are amphiphilic molecules consisting of a hydrophobic aromatic part linked to a hydrophilic group by an ester or amide linkage. They are weak bases and are usually available as salts, which increases their solubility and stability. Once administered, LAs exist in the body either...
Local anesthetics are amphiphilic molecules consisting of a hydrophobic aromatic part linked to a hydrophilic group by an ester or amide linkage. They are weak bases and are usually available as salts, which increases their solubility and stability. Once administered, LAs exist in the body either...
3.3K
01:46Nuclear Localization Signals and Import
7.7K
Proteins targeted to the nucleus carry short stretches of amino acid sequences called the nuclear localization signal or NLS. Classical nuclear localization signals are of two types: monopartite and bipartite NLS. Monopartite classical NLS (cNLS) consists of a single cluster of 4-8 amino acids. Bipartite cNLS consists of two clusters of 2-3 amino acids and a 9-12 residue long proline-rich linker bridging the two clusters. Signal clusters are rich in positively charged amino acids such as...
7.7K
01:22Absolute and Local Extreme Values
58
The highest and lowest values of a function, relative to a reference axis, are known as extreme values. These include absolute maximum and absolute minimum values, which represent the highest and lowest points the function reaches across its entire domain. Within a restricted portion of the function, the highest and lowest values are referred to as local maximum and local minimum values, respectively.Periodic functions, such as sine and cosine, show extreme values at infinitely many points due...
58