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Recombinant murine gamma interferon inhibits Chlamydia trachomatis serovar L1 in vivo
G M Zhong1, E M Peterson, C W Czarniecki
1Department of Pathology, University of California Irvine 92717.
Infection and Immunity
|January 1, 1988
Abstract:
Chlamydia trachomatis serovar L1 injected intravenously in mice resulted in systemic nonlethal infections of the animals. Treatment of mice with recombinant murine gamma interferon resulted in a decrease in the number of infectious C. trachomatis organisms recovered from the lungs, spleens, and livers as well as in a decrease of the inflammatory reaction in those organs when assessed 3 and 5 days after challenge.