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Updated: Jan 23, 2026

Application of Optical Coherence Tomography to a Mouse Model of Retinopathy
Published on: January 12, 2022
[Applications of optical coherence tomography in glaucoma]
V A Machekhin1, O L Fabrikantov1, V A L'vov2
1Tambov branch of S. Fyodorov Eye Microsurgery Federal State Institution, 1 Rasskazovskoe highway, Tambov, Russian Federation, 392000; Tambov State University named after G.R. Derzhavin, Medical Institute, 93 Sovetskaya St., Tambov, Russian Federation, 392000.
Abstract:
The article reviews literature on optical coherence tomography (OCT) - one of the modern methods of early diagnostics of primary open-angle glaucoma, which has won great popularity among Russian and foreign ophthalmologists. In addition to a summary of the history of the emergence and development of this method, the main purpose was to compare the investigation results and the analysis of the optic disc as the main target subjected to pathological alterations in glaucoma development. Most of the studies comparing the diagnostic capabilities of OCT and Heidelberg retinal tomography (HRT) in the early detection of glaucoma show equivalence of these methods. On the other hand, OCT allows performing subtler structural analysis of the retina, whereas HRT provides more accurate analysis of internal parameters of the optic disc.
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