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Updated: Jan 23, 2026

Application of Optical Coherence Tomography to a Mouse Model of Retinopathy
Published on: January 12, 2022
[Applications of optical coherence tomography in glaucoma].
V A Machekhin1, O L Fabrikantov1, V A L'vov2
1Tambov branch of S. Fyodorov Eye Microsurgery Federal State Institution, 1 Rasskazovskoe highway, Tambov, Russian Federation, 392000; Tambov State University named after G.R. Derzhavin, Medical Institute, 93 Sovetskaya St., Tambov, Russian Federation, 392000.
Optical coherence tomography (OCT) is a popular tool for early glaucoma diagnosis. Studies show OCT and Heidelberg retinal tomography (HRT) are comparable for early glaucoma detection.
Area of Science:
- Ophthalmology
- Medical Imaging
Background:
- Primary open-angle glaucoma requires early detection for effective management.
- Optical coherence tomography (OCT) has emerged as a significant diagnostic tool in ophthalmology.
- Glaucoma's pathological alterations primarily affect the optic disc.
Purpose of the Study:
- To review literature on Optical coherence tomography (OCT) for early diagnosis of primary open-angle glaucoma.
- To compare the diagnostic capabilities of OCT with Heidelberg retinal tomography (HRT).
- To analyze the investigation results concerning the optic disc in glaucoma development.
Main Methods:
- Literature review of studies comparing OCT and HRT.
- Analysis of optic disc structural changes in glaucoma.
- Comparison of retinal and optic disc parameter assessments.
Main Results:
- Most studies indicate OCT and HRT have equivalent diagnostic capabilities for early glaucoma detection.
- OCT enables more detailed structural analysis of the retina.
- HRT offers more precise analysis of internal optic disc parameters.
Conclusions:
- OCT is a valuable and increasingly popular method for early glaucoma diagnosis.
- Both OCT and HRT are effective, with complementary strengths in analyzing glaucoma-related changes.
- Further research can refine the comparative utility of these imaging modalities.
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