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Measurements of Motor Function and Other Clinical Outcome Parameters in Ambulant Children with Duchenne Muscular Dystrophy
Published on: January 12, 2019
[PSORIATIC ARTHRITIS IN CHILDREN: CHARACTERISTICS OF THE CLINICAL PICTURE]
S Chebysheva1, E Zholobova1, K Aleksanyan1
1Institute of children's health, Department of children's diseases; University children's clinical hospital; FIRST Moscow state medical University. I. M. SechenovMinistry of health of Russia (Sechenov University), Moscow, Russia.
Psoriatic arthritis (PSA) in children often begins around age 6.5 with skin and joint symptoms. Unlike typical findings, symmetric rheumatoid-like arthritis and periarticular osteoporosis are common in pediatric PSA.
Area of Science:
- Pediatrics
- Rheumatology
- Dermatology
Background:
- Psoriatic arthritis (PSA) is a chronic inflammatory disease affecting joints and skin.
- Understanding the specific clinical course in pediatric populations is crucial for effective management.
Purpose of the Study:
- To delineate the characteristic clinical features of psoriatic arthritis in children.
- To identify patterns in disease onset, symptom progression, and joint involvement in pediatric PSA.
Main Methods:
- Retrospective analysis of 83 pediatric patients diagnosed with psoriatic arthritis.
- Evaluation of the timing of skin and articular syndrome development.
- Assessment of disease onset patterns, including age of debut and initial symptoms.
Main Results:
- The majority of pediatric PSA cases debut around 6.5 years of age.
- Disease onset frequently involves initial skin lesions followed by joint involvement.
- Common presentations include asymmetric oligoarthritis, spondylitis with peripheral joint involvement, and a notable prevalence of symmetric rheumatoid-like arthritis and periarticular osteoporosis, contrasting with existing literature.
Conclusions:
- Pediatric psoriatic arthritis exhibits distinct clinical features compared to adult forms.
- Early onset and specific patterns of joint and skin manifestations, including rheumatoid-like arthritis and osteoporosis, characterize childhood PSA.
- These findings necessitate tailored diagnostic and therapeutic approaches for pediatric patients.
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