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Updated: Aug 16, 2026
04:28
Lung Tumor Cell Recruitment Assay
Published on: February 26, 2019
CXCR3-CXCL9: It's All in the Tumor
Etienne Humblin1, Alice O Kamphorst2
1Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Immunity
|June 20, 2019
Abstract:
In this issue of Immunity, Chow et al. (2019) show that the CXCR3-CXCL9 axis is required for reinvigoration of intratumoral CD8+ T cell responses in response to PD-1 blockade and demonstrate that local guidance to dendritic cells, rather than recruitment of T cells into the tumor, underlies the importance of this chemokine axis.
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