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Author Spotlight: Enhancing Candida albicans Detection in Catheter Infections Using Fluorescent Protein Tagging
Published on: March 22, 2024
mSphere of Influence: a Systematic Approach To Dissect Virulence Traits in Candida albicans
1Interdisciplinary Center for Clinical Research, University Hospital Würzburg, Würzburg, Germany christian.perez@uni-wuerzburg.de.
Abstract:
J. Christian Pérez studies the interplay between Candida albicans and the mammalian host. In this mSphere of Influence article, he reflects on how "Systematic screens of a Candida albicans homozygous deletion library decouple morphogenetic switching and pathogenicity" (S. M. Noble, S. French, L. A. Kohn, V. Chen, et al., Nat Genet 42:590-598, 2010, https://doi.org/10.1038/ng.605) provided tools and a blueprint for open-ended genetic screens in an organism that had been a challenge for genetic manipulation.
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