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Updated: Jan 23, 2026

Electroeluting DNA Fragments
Published on: September 5, 2010
Multiplex optical detection and quantification of DNA fragments by metallo-peptide assemblies
Abhijit Saha1,2, Meital Reches3,4
1Institute of Chemistry, The Hebrew University of Jerusalem, Edmond J. Safra Campus, Givat Ram, Jerusalem, 9190401, Israel.
Abstract:
Rapid detection of infectious agents such as bacteria and viruses are important for proper health management, agriculture and homeland security. This paper presents a multiplex DNA detection system self-assembled by a metallo-peptide complex. Within five minutes, the system can simultaneously detect multiple DNA fragments, without any need for their separation. The presence of proteins in the sample does not harm the detection capabilities of the system, which can discriminate even between one base-pair mismatch and can perform at concentrations as low as 200 pM.
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