Related Experiment Video
Updated: Jan 23, 2026

In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography
Published on: July 24, 2020
Regional Differences of Choroidal Structure Determined by Wide-Field Optical Coherence Tomography
Naoko Kakiuchi1, Hiroto Terasaki1, Shozo Sonoda1
1Department of Ophthalmology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan.
Purpose:
To compare the submacular to the perimacular choroidal structure in images obtained by wide-field optical coherence tomography (OCT).
Methods:
Thirty eyes of 30 healthy volunteers (15 men) were studied. Twelve wide-field radial circumferential scans were recorded with enhanced depth imaging OCT from the macular and perimacular zones. The sizes of the luminal and stromal areas of the choroid were determined. The two zones were subdivided into the superior, inferior, nasal, and temporal sectors. The total choroidal area, the luminal and stromal areas, and the luminal ratio of each sector were compared.
Results:
All of the choroidal structural parameters analyzed in the present study were largest in the superior sector followed by the temporal, inferior, and nasal sectors. The coefficients of variation were larger in the perimacular zone than in the macular zone: The luminal ratio in the macular zone varied by 1.2%, and that in perimacular zone varied by 4.2%.
Conclusions:
The variations in the ratios of the luminal areas of the choroid in the wide-field OCT images are slight in the macular zone but considerable in the perimacular zone.
Related Concept Videos
Determining Electric Field From Electric Potential
In general, regardless of whether the electric field is uniform, it points in the direction of decreasing potential because the force on a positive...
The Eukaryotic Promoter Region
IR Frequency Region: Fingerprint Region
Difference from Background: Limit of Detection
The LOD indicates the presence or absence...
Electric Potential and Potential Difference
When a test charge moves from the initial to the final position, the electric potential difference between those positions is defined as the ratio of the change in the potential energy to the charge on the...
Identifying Statistically Significant Differences: The F-Test

