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Related Concept Videos

Archival Research01:40

Archival Research

17.1K
Some researchers gain access to large amounts of data without interacting with a single research participant. Instead, they use existing records to answer various research questions. This type of research approach is known as archival research. Archival research relies on looking at past records or data sets to look for interesting patterns or relationships. For example, a researcher might access the academic records of all individuals who enrolled in college within the past ten years and...
17.1K
DNA Base Pairing02:27

DNA Base Pairing

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Erwin Chargaff’s rules on DNA equivalence paved the way for the discovery of base pairing in DNA. Chargaff’s rules state that in a double-stranded DNA molecule,
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DNA Base Pairing02:27

DNA Base Pairing

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Base-pairing and DNA Repair02:27

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Base Excision Repair01:54

Base Excision Repair

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One of the common DNA damages is the chemical alteration of single bases by alkylation, oxidation, or deamination. The altered bases cause mispairing and strand breakage during replication. This type of damage causes minimal change to the DNA double helix structure and can be repaired by the base excision repair (BER) pathways. BER corrects damaged DNA sequences by removing the damaged base and restoring the original base sequence using the complementary strand as a template.
The first step of...
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Lewis Acids and Bases02:33

Lewis Acids and Bases

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In 1923, G. N. Lewis proposed a generalized definition of acid-base behavior in which acids and bases are identified by their ability to accept or to donate a pair of electrons and form a coordinate covalent bond.
A coordinate covalent bond (or dative bond) occurs when one of the atoms in the bond provides both bonding electrons. For example, a coordinate covalent bond occurs when a water molecule combines with a hydrogen ion to form a hydronium ion. A coordinate covalent bond also results when...
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Updated: Jan 23, 2026

Quasi-light Storage for Optical Data Packets
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Carbon-based archiving: current progress and future prospects of DNA-based data storage.

Zhi Ping1, Dongzhao Ma1, Xiaoluo Huang1

  • 1Guangdong Provincial Key Laboratory of Genome Read and Write, Shenzhen Engineering Laboratory for Innovative Molecular Diagnostics, Guangdong Provincial Academician Workstation of BGI Synthetic Genomics, BGI-Shenzhen, Shenzhen 518083, China.

Gigascience
|June 21, 2019
PubMed
Summary

Data scientists are exploring DNA-based storage as a stable, space-efficient alternative to traditional media. This review covers DNA coding schemes and media types for future digital information storage.

Keywords:
in vitro DNA digital storagein vivo DNA digital storageDNA digital storagebinary-DNA encoding scheme

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Area of Science:

  • Biotechnology
  • Data Science
  • Information Storage

Background:

  • The exponential growth of digital data necessitates advanced storage solutions beyond current magnetic and optical media.
  • Existing storage technologies face limitations in capacity and long-term stability for massive datasets.
  • DNA offers a highly condensed and stable medium with significant potential for future data storage.

Purpose of the Study:

  • To review state-of-the-art methods in DNA-based data storage.
  • To summarize digital-to-DNA coding schemes and media types.
  • To provide an overview of recent progress and future prospects in DNA data storage.

Main Methods:

  • Literature review of current DNA data storage technologies.
  • Analysis of digital-to-DNA encoding and decoding strategies.
  • Examination of various media types employed for DNA data storage.

Main Results:

  • DNA-based data storage presents a promising approach for high-density, long-term information preservation.
  • Various coding schemes have been developed to efficiently translate digital data into DNA sequences.
  • Recent advancements demonstrate the feasibility and increasing efficiency of DNA data storage systems.

Conclusions:

  • DNA data storage is emerging as a viable and powerful technology for addressing future data storage challenges.
  • Continued research in coding schemes and synthesis/sequencing technologies will further enhance DNA storage capabilities.
  • The unique properties of DNA position it as a key medium for the future of digital information archiving.