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Updated: Jan 23, 2026

Measuring Local Anaphylaxis in Mice
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Anaphylaxis - Lessons learnt when East meets West.

Elizabeth H Tham1,2, Agnes S Y Leung3, Punchama Pacharn4

  • 1Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.

Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology
|June 21, 2019
PubMed
Summary
This summary is machine-generated.

Anaphylaxis incidence is rising globally, with distinct triggers in Asia compared to Western regions. Adrenaline use for anaphylaxis treatment remains concerningly low worldwide.

Keywords:
Asiaanaphylaxisepidemiologyfood allergy

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Area of Science:

  • Allergy and Immunology
  • Epidemiology
  • Public Health

Background:

  • Allergic disorders are rapidly increasing globally.
  • Understanding anaphylaxis epidemiology is crucial due to rising prevalence.
  • Existing data suggests an increasing trend in anaphylaxis incidence worldwide.

Purpose of the Study:

  • To analyze the epidemiology of anaphylaxis globally.
  • To compare anaphylaxis triggers and management between Asia and Western populations.
  • To identify gaps in data collection and areas for future research.

Main Methods:

  • Review of existing literature on anaphylaxis incidence and prevalence.
  • Analysis of reported anaphylaxis triggers across different geographical regions.
  • Assessment of first-line treatment practices, specifically adrenaline use.

Main Results:

  • Anaphylaxis incidence ranges from 60-950 cases per 100,000 population in Europe, US, and Australia.
  • Lifetime prevalence of anaphylaxis is estimated between 0.05%-2%.
  • Asian populations show different anaphylaxis triggers (e.g., shellfish, wheat, traditional medications) compared to Western populations.
  • Low adrenaline usage for anaphylaxis treatment is a consistent concern globally.

Conclusions:

  • There is a need for standardized anaphylaxis data collection and reporting protocols.
  • Understanding regional differences in triggers and management is vital for targeted interventions.
  • Further research is required to address the burden of anaphylaxis and improve primary preventive strategies.